kappa light chain

kappa light chain

one of two kinds of smaller peptide chains present in an immunoglobulin molecule. See also lambda light chain.
References in periodicals archive ?
Laboratory values from the past year were significant for increased kappa light chain immunoglobulin, a finding consistent with her amyloidosis.
Further immunofixation with IgD and IgE antisera identified IgD-kappa paraproteinaemia and kappa light chain in the urine.
Plasma cells expressed IgG and showed a kappa light chain restriction.
IMMUNOHISTOCHEMISTRY (IHC): Neoplastic lymphoid cells were CD 20, PAX5, CD10 and Bcl2 positive and Kappa light chain restriction.
9 g/dL, increased serum IgM level of 2340 mg/L (normal range: 56-352 mg/dL), free kappa light chain level of 7.
Fourteen cryoglobulins were immune complexes containing IgM, IgG and kappa light chain, and three had only one type of immunoglobulin (see Table 3).
KA upregulated and UR down-regulated the expressions of nuclear factor of kappa light chain (Nfkbia) gene and IL-1[beta] gene, which are associated with inflammation.
Crystal-storing histiocytosis: a disorder occurring in plasmacytic tumors expressing immunoglobulin kappa light chain.
The VelocImmune mice have all human heavy chain immunoglobulin genes and kappa light chain genes, each linked to endogenous mouse constant regions.
In a study including juvenile idiopathic arthtiris (JIA) patients, abnormalities in the peripheral B cell pool, namely kappa light chain repertoire were observed and the possibility of disturbance in B cell tolerance by multiple pathogenic mechanisms in JIA was highlighted.
Sensitive probes include: Epstein-Barr encoded RNA (EBER), kappa light chain, lambda light chain, dual kappa/lambda, IgA-alpha heavy chain, IgG-gamma heavy chain, IgM-mu heavy chain, and ribosomal RNA (positive control).