kaolin clotting time

kaolin clotting time (KCT),

a sensitive test of platelet-poor plasma for detecting lupus anticoagulants in mixtures of plasma taken from patients and from control groups; kaolin initiates clotting through the contact factors and subsequently involves other factors in the intrinsic pathway of coagulation.

ka·o·lin clot·ting time

(KCT) (kā'ō-lin klot'ing tīm)
A sensitive test of platelet-poor plasma for detecting lupus anticoagulants in mixtures of plasmas taken from patients and from control groups; kaolin initiates clotting through the contact factors and subsequently involves the other factors in the intrinsic pathway of coagulation.
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References in periodicals archive ?
The effect is more pronounced with reagents whose phospholipid content is relatively low (12) and may be greater with the kaolin clotting time (KCT) than with the dilute Russell viper venom test (dRVVT) (14).
Kaolin clotting time and dilute Russell viper venom time distinguish between prothromb-independent and beta 2-glycoprotein I-dependent anti phospholipid antibodies.
It is recommended that LA be initially screened using tests such as modified activated partial thromboplastin time (APTT), kaolin clotting time (KCT), and dilute Russell's viper venom time (dRVVT).
Instead, use the kaolin clotting time or other tests with increased sensitivity to the presence of the factor inhibiting phospholipid-dependent reactions in the clotting test, Dr.
Silica clotting time (SCT) has been described as a specific and sensitive alternative to kaolin clotting time for detecting LA (6-9).