KLK8

(redirected from kallikrein-related peptidase 8)

KLK8

A gene on chromosome 19q13.3 that encodes a serine protease that catalyses the degradation of casein, fibrinogen, kininogen, fibronectin and collagen type IV. It cleaves L1CAM in response to increased neural activity, and induces neurite outgrowth and fasciculation of cultured hippocampal neurons.
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References in periodicals archive ?
We have examined the prognostic value of alternative mRNA variants of the KLK8 [6] (kallikrein-related peptidase 8) gene.
Expression and prognostic significance of kallikrein-related peptidase 8 protein levels in advanced ovarian cancer by using automated quantitative analysis.
[6] Human genes: KLK8, kallikrein-related peptidase 8; KLK3, kallikrein-related peptidase 3; KLK5, kallikrein-related peptidase 5; KLK6, kallikrein-related peptidase 6; KLK7, kallikrein-related peptidase 7; KLK10, kallikrein-related peptidase 10; KLK11, kallikrein-related peptidase 11; KLK13, kallikrein-related peptidase 13; KLK14, kallikrein-related peptidase 14; ERBB4, v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian); LOX, lysyl oxidase.