KLK1

(redirected from kallikrein-1)

KLK1

A gene on chromosome 19q13.3 that encodes a serine protease with diverse physiological functions, which may also have a role in carcinogenesis. KLK1 releases the vasoactive peptide Lys-bradykinin from low molecular weight kininogen.
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The investigators focused on three proteins whose levels increased in OSA-uromodulin, orosomucoid-1, and urocortin-3--and one protein whose levels decreased, kallikrein-1.
Three proteins increased in OSA--uromodulin, orosomucoid-1, and urocortin-3--and one protein decreased, kallikrein-1.
Identification and androgen-regulated expression of two major human glandular kallikrein-1 (hGK-1) mRNA species.
(b) Full gene names are as follows: hPRK, human pancreatic/renal kallikrein; hGK-1, human glandular kallikrein-1; KLK-L, kallikrein-like; EMSP1, enamel matrix serine proteinase 1; HSCTE, human stratum corneum tryptic enzyme; HSCCE, human stratum corneum chymotryptic enzyme; TADG-14, tumor-associated, differentially expressed gene-14; NES1, normal epithelial cell-specific 1 gene; TLSP, trypsin-like serine protease; PRSS, protease serine; PRSSL, protease serine-like.