KLK8

(redirected from kallikrein 8)

KLK8

A gene on chromosome 19q13.3 that encodes a serine protease that catalyses the degradation of casein, fibrinogen, kininogen, fibronectin and collagen type IV. It cleaves L1CAM in response to increased neural activity, and induces neurite outgrowth and fasciculation of cultured hippocampal neurons.
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References in periodicals archive ?
Human kallikrein 8 protease confers a favorable clinical outcome in non-small cell lung cancer by suppressing tumor cell invasiveness.
Human kallikrein 8 (hK8/TADG-14) expression is associated with an early clinical stage and favorable prognosis in ovarian cancer.
Functional characterization of the human-specific (type II) form of kallikrein 8, a gene involved in learning and memory.
Human kallikrein 8 protein is a favorable prognostic marker in ovarian cancer.
Human kallikrein 8: immunoassay development and identification in tissue extracts and biological fluids.