TaqMan gene expression assays used were Hs00160519_m1 (kallikrein 6, KLK6), Hs00173611_m1 (kallikrein 10, KLK10), Hs00234579_m1 (matrix metalloproteinase 9, MMP9) and Hs99999905_m1 (glyceraldehyde 3-phosphate dehydrogenase, GAPDH).
In the conditioned cell culture medium from UMSCC1 cells with higher expression of miR-375, the most significantly reduced secreted proteases were a group of serine proteases known as kallikreins: kallikrein 5, kallikrein 6, kallikrein 10, and kallikrein 13.
Measurement of Kallikrein 6 (KLK6) in Circulating Plasma by ELISA.
Chung et al., "Up-regulation and clinical significance of serine protease kallikrein 6 in colon cancer," Cancer, vol.
Transcriptional upregulation of human tissue kallikrein 6
in ovarian cancer: clinical and mechanistic aspects.
Immunofluorometric assay of human kallikrein 6 (zyme/protease M/neurosin) and preliminary clinical applications.
Purification of human kallikrein 6 from biological fluids and identification of its complex with alpha(1)-antichymotrypsin.
Human kallikrein 6 (hK6): a new potential serum biomarker for diagnosis and prognosis of ovarian carcinoma.
 Nonstandard abbreviafions: CaP, prostate cancer; ACN, acetonitrile; CM, condifioned medium; FPLC, last performance liquid chromatography; hK5, human kallikrein 5 protein; hK6, human kallikrein 6 protein; hK11, human kallikrein 11 protein; MS/MS, tandem mass spectrometry; PSA, prostate-specific anfigen; SAX, strong anion exchange; TBST, Tris-buffered saline with Tween 20.
Human kallikrein 6
(zyme/protease M/neurosin): a new serum biomarker of ovarian carcinoma.
The human kallikrein 6
(KLK6) gene, which encodes for hK6 protein, was cloned independently by three groups.
The spectrum of human kallikrein 6
(zyme/ protease M/neurosin) expression in human tissues as assessed by immunohistochemistry.