KLK4

(redirected from kallikrein 4)

KLK4

A gene on chromosome 19q13.41 that encodes a serine protease expressed in the prostate.

Molecular pathology
Mutations of KLK4 cause amelogenesis imperfecta hypomaturation type 2A1.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Human kallikrein 4: quantitative study in tissues and evidence for its secretion into biological fluids.
Detection of human kallikrein 4 in healthy and cancerous prostatic tissues by immunoflurometry and immunohistochemistry.
Kallikrein 4 (KLK4), a new member of the human kallikrein gene family is up-regulated by estrogen and progesterone in the human endometrial cancer cell line, KLE.
[6] Human genes: KLKI, kallikrein 1, renal/pancreas/salivary; KLK2, kallikrein 2, prostatic; KLK3, kallikrein 3 (prostate-specific antigen); and KLK4, kallikrein 4 (prostase, enamel matrix, prostate).
The human kallikrein 4 gene (KLK4)5 is a member of the human kallikrein family.
Human kallikrein 4 (KLK4) is highly expressed in serous ovarian carcinomas.
Kallikrein 4 is associated with paclitaxel resistance in ovarian cancer.
Kallikrein 4 is a predominantly nuclear protein and is over-expressed in prostate cancer.
Kallikrein 4 is a predominantly nuclear protein and is overexpressed in prostate cancer.
Detection of human kallikrein 4 in healthy and cancerous prostattc tissues by immunofluorometry and immunohistochemistry.
Kallikrein 4 (KLK4), a new member of the human kallikrein gene family, is upregulated by estrogen and progesterone in the human endometrial cancer cell line, KLE.