KLK10

(redirected from kallikrein 10)

KLK10

A gene on chromosome 19q13 that encodes a serine protease which is expressed in the breast, ovary and prostate; it has a tumour suppressor role in breast and prostate cancer.
References in periodicals archive ?
In the conditioned cell culture medium from UMSCC1 cells with higher expression of miR-375, the most significantly reduced secreted proteases were a group of serine proteases known as kallikreins: kallikrein 5, kallikrein 6, kallikrein 10, and kallikrein 13.
Elevated miR-375 Expression in HNSCC Cells Regulates Kallikrein 6, Kallikrein 10, and MMP-9 mRNA Expression
The qPCR measurements were used to evaluate the impact of elevated miR-375 expression on the mRNA expression of the commonly regulated proteases, kallikrein 6 (KLK6), kallikrein 10 (KLK10), and matrix metalloproteinase 9 (MMP9).
Three dysregulated miRNAs control kallikrein 10 expression and cell proliferation in ovarian cancer.
The serum concentration of human kallikrein 10 represents a novel biomarker for ovarian cancer diagnosis and prognosis.
The first of these assays is for human kallikrein 10 (hK10).
The concentration of the kallikrein 10 (KLK10) in NAF samples was measured by a sandwich-type immunoassay as previously described (13).
Immunofluorometric assay of human kallikrein 10 and its identification in biological fluids and tissues.
Steroid hormone regulation of the human kallikrein 10 (KLK10) gene in cancer cell lines and functional characterization of the KLK10 gene promoter.
She cloned and characterized a novel serine protease gene, human tissue kallikrein 10 (hK10), and developed an immunoassay to measure hK10 protein concentrations in biological fluids and tissue extracts.
CpG methylation as a basis for breast tumor-specific loss of NES1/ kallikrein 10 expression.
Prognostic value of human kallikrein 10 expression in epithelial ovarian carcinoma.