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juvenile xanthogranuloma a benign, self-limited disorder of infants and children, usually present at birth, manifested by the development of single or multiple papules or nodules, which may be yellow, pink, orange, or reddish brown in color, found typically on the scalp, face, proximal extremities, or trunk; involvement of mucous membranes, viscera, eye, and other organs may also occur.
single or multiple reddish to yellow papules or nodules, usually found in young children, consisting of dermal infiltration by histiocytes and Touton giant cells, with increasing fibrosis.
a skin disorder characterized by groups of yellow, red, or brown papules or nodules on the extensor surfaces of the arms and legs and, in some cases, on the eyeball, meninges, and testes. The lesions typically appear in infancy or early childhood and usually disappear in a few years.
juvenile xanthogranulomaJuvenile lipogranuloma, nevoxanthoendothelioma A yellowish tumor of early childhood, involving the face, head, neck, extremities Prognosis Spontaneous involution
xanthogranuloma, juvenile (JXG)
A benign proliferation of single or multiple, small yellowish-brown papules or nodules in the skin and the anterior uvea, especially the iris. The condition mainly appears in young children, although it may occur in adults. The lesions consist of dermal infiltration by histiocytes, lymphocytes, eosinophils and Touton giant cells. The skin lesions increase in size and number but eventually regress spontaneously into an atrophic scar, otherwise they may need to be treated by excision or corticosteroid injection. In the eye it is commonly associated with hyphaemia (in the anterior chamber), uveitis and secondary glaucoma with visual loss. Therapy includes topical and systemic corticosteroids. Syn. juvenile nevoxanthoendothelioma.