joint-space narrowing

joint-space narrowing

The radiographic appearance of a joint that has lost its surface cartilage. The bones in the joint are not separated by the normal or usually observed distance. They appear to be too close to each other, and they are often eburnated or sclerotic.
References in periodicals archive ?
X-rays show joint-space narrowing with OA, but no erosions or cysts.
The investigational drug also seemed to slow joint-space narrowing, compared with baseline values, with the suggestion that it may even increase joint space width.
Participants needed to have a knee OA incidence with a K&L grade of at least 2; incidence of clinical knee OA according to clinical and radiographic American College of Rheumatology criteria; or joint-space narrowing of at least 1.0 mm.
Arthroscopic debridement is not recommended for patients with advanced arthritis, significant joint-space narrowing, marked fibrosis, or mechanical deformity.
But two trials concurrent with GAIT reported less knee joint-space narrowing over years of taking 800 mg of chondroitin daily.
The arthropathy superficially resembles degenerative joint disease, with joint-space narrowing, sclerosis, and osteophytosis; but, in hemochromatosis, it reveals definite characteristics in its distribution and appearance that enable it to be recognized on radiographic examination.
Those who took this nutrient had no increase in joint-space narrowing. Those who took the placebo, did.
Those taking glucosamine showed less joint-space narrowing on X-rays than those taking placebos.
The difference in total 24-month progression between the two treatment arms was statistically significant for total SVdH score and erosion score, and for the extent of joint-space narrowing. In addition, the difference in total SVdH score between months 12 and 24 for the two treatment arms was statistically significant.
Plain radiography may show joint-space narrowing, osteophyte formation, and/or subchondral sclerosis, although radiography is often normal in early disease.
In the first trial, the 106 patients on placebo had progressive joint-space narrowing, with a mean joint-space loss after 3 years of -0.31 mm (95% = -0.48 to -0.13).

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