GIF

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macrophage migration inhibitory factor

A 25-kD proinflammatory lymphokine, produced by T cells in response to antigenic stimulus, which inhibits macrophage migration.

Gene
MMIF is encoded by MIF on chromosome 22q11.23.

Activities
Cell-mediated immunity, inflammation and regulation of macrophage function in host defence by suppressing the anti-inflammatory effects of glucocorticoids.
 
Mechanism
Increases intracellular cAMP, polymerises microtubules, stops macrophage progression.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
So, like the women of my family I am in the kitchen at midnight scrubbing pots with Jiff.
For instance, you may have seen the GIF format (pronounced jiff), a way of storing picture files compactly.
Where don Quijote asks to see the religious figures in II, 48, one of the men says: "Just wait a jiff and you'll see with your own two eyes" (874).
As for support to NGOs providing medical treatment to Afghan refugees, Japan will give some 60 million yen to the Japan International Friendship and Welfare Foundation (JIFF) and about 38 million yen to the Association of Medical Doctors of Asia (AMDA), the ministry said.
They work with the Japan International Friendship and Welfare Foundation (JIFF), a nongovernmental organization.
(1) Jifjafa ia variously spelt Jifjaffa, Jif-Jaffa, Jif Jaffa, Jif Jafa, Jiff Jaffa, Bit el Jifjafa, Bir el Jifjaffa and Gifgaffa in contemporary documents and maps.
Sparks from a bench grinder can pit and burn a wood bench top in a jiff, and may even ignite accumulated shop dust behind the grinder.
Jiri Priban, Legitimacy and Legality After the Velvet Revolution, in THE RULE OF LAW IN CENTRAL EUROPE 29, 45-46 (Jiff Priban & James Young eds., 1999) (citation omitted).
The Jiff "V" Sharp (say it fast) is a handy little plastic gizmo with some carbide steel inserts in a "V" shape.
And when he briefly drops out of circulation, what should fate throw Bowfinger's way but Jiff, a lookalike so dumb he can be convinced the highway traffic are all stunt drivers.
It would be hard to miss popularity with Steve Martin in the title role as a producer-director who has little going for him except an insane self-confidence, and Eddie Murphy as both Kit Ramsey, the unavailable star around whom Bowfinger shoots his movie without Kit knowing it, and Jiff Ramsey, his goofy-looking brother with glasses who is down on his luck.