ivermectin


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i·ver·mec·tin

(ī'vĕr-mek'tin),
A semisynthetic macrolide antibiotic of the avermectin family of compounds, effective in the treatment of filariasis and many other parasites. The drug destroys Onchocerca microfilaria and Filaria bancrofti. Derived from the soil bacterium, Streptomyces avermitilis. Approved by the FDA for the treatment of scabies by topical administration. Widely used in veterinary medicine in a number of species for control of ectoparasites and endoparasites. Unusual sensitivity (increased toxicity, and sometimes death) in collie-type breeds is well documented.

ivermectin

(ī′vər-mĕk′tĕn)
n.
An anthelmintic and acaricide used to treat parasitic infections in livestock, to prevent heartworm infection in dogs, and to treat onchocerciasis, intestinal strongyloidiasis, and head lice in humans.

ivermectin

A drug used to kill MICROFILARIA in the treatment of ONCHOCERCIASIS and other microfilarial diseases. Ivermectin has also been used to treat severe SCABIES in elderly institutionalized people, but an unusually high death-rate in this group cast doubt on the safety of the application. The drug is on the WHO official list.

ivermectin

parasiticide; single-dose treatment for scabies

onchocerciasis 

A disease caused by infestation with the filarial worm (Onchocerca volvulus) spread by blackflies. It is common in tropical Africa and Central America, especially in areas near rivers. Large numbers of microfilariae are present on the skin and often enter the eye. The patient initially complains of itching, but blindness occurs as a result of chorioretinitis and optic neuritis. The disease is treated successfully with ivermectin. Syn. onchocercosis; river blindness.

ivermectin

an avermectin with broad activity against many helminths and arthropods. A broad-spectrum anthelmintic, acaricide and insecticide, used orally, subcutaneously and as a pour-on.
References in periodicals archive ?
Several antihelminthic drugs against Serratospiculum species have been described, such as febendazole, levamisole, mebendazole, moxidectin, thiabendazole, melarsomine combined with ivermectin, and ivermectin alone.
Nematodes infected buffalo treated with Ivermectin: The Ivermectin treatment showed complete elimination of ostertagia, Haemonchus, Trichostrongylus, Nematodirus, while Trichuris showed a low infection.
Patients with paralytic ileus can have difficulty absorbing oral ivermectin due to tissue edema.
Treatment of humpsore-Stephanofilariasis of cattle with ivermectin.
The answer looms larger than we might think: Ivermectin may be doing to dung beetles what DDT did to birds, what diclofenac did to vultures in India, or what neonicotinoid insecticides are thought to be doing to honeybees, now in decline worldwide.
4,5 Permethrin, benzyl benzoate, crotamiton, lindane, and ivermectin are the various drugs used for treating scabies.
Efficacy of different dosages of ivermectin injectable against Hypodermaspp.
He reported serving as a consultant to half a dozen pharmaceutical companies, including Galderma, which markets ivermectin cream and brimonidine gel, and Bayer, which markets azelaic acid foam.
2 mg/kg) of ivermectin was an effective treatment for myiasis.
Ivermectin forms the core strategy in eliminating the neglected tropical disease, with clinical trials in patients showing a single dose was sufficient to kill all of the parasites.
To determine the course of treatment, repeat O&Ps were done every 72 hours and ivermectin was continued until stool O&Ps were negative for 2 weeks.