isozyme


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isoenzyme

 [i″so-en´zīm]
any of several forms of an enzyme that all catalyze the same reaction but may differ in reaction rate, inhibition by various substances, electrophoretic mobility, or immunologic properties. Several enzymes, particularly alkaline phosphatase, lactate dehydrogenase, and creatine kinase, have clinically important isoenzymes. Isoenzymes are separated by electrophoresis, and the pattern indicates which damaged organ has released the enzymes.

i·so·en·zyme

(ī'sō-en'zīm),
An enzyme (one of a group) that catalyze the same reaction but may be differentiated by variations in physical properties, such as isoelectric point, electrophoretic mobility, kinetic parameters, or modes of regulation, for example, lactate dehydrogenase, a tetramer composed of varying amounts of α and β subunits (that is, 4α, 3α + 1β, 2α + 2β, 1α + 3β, and 4β).
Synonym(s): isozyme

isozyme

(ī′sə-zīm′)
n.
An isoenzyme.

i′so·zy′mic adj.

i·so·en·zyme

(ī'sō-en'zīm)
One of a group of enzymes that catalyze the same reaction but may be differentiated by variations in physical properties, such as isoelectric point, electrophoretic mobility, kinetic parameters, or modes of regulation.

isozyme

see ISOENZYME.
References in periodicals archive ?
Supuran, "Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX," Bioorganic & Medicinal Chemistry Letters, vol.
LDH isozymes LDH-A4, LDH-A3B1, LDH-A2B2 (Zhu et al., 2009) in skeletal muscle suggest that pika skeletal muscle mainly relies on the aerobic respiration.
KEYWORDS: Dicranopteris linearis, Desiccation, Antioxidant enzymes, Isozymes expression
Peroxidase isozymes: Electrophoretic pattern of peroxidase showed eight bands (Fig.
Total U-LDH activity and its isozyme patterns during pre-IVIG phase were compared between the IVIG responders and nonresponders in the KD group (Table 3).
To obtain reliable isozyme profiles, several individuals per population and species were analyzed, although that enzyme activity depended on the freshness of samples upon arrival to the laboratory.
* The report provides a snapshot of the global therapeutic landscape for Corticosteroid 11-Beta-Dehydrogenase Isozyme 1 (11-Beta-Hydroxysteroid Dehydrogenase 1 or Short Chain Dehydrogenase/Reductase Family 26C Member 1 or 11-DH or 11-beta-HSD1 or HSD11B1 or EC 1.1.1.146)
The presence of an ALP isozyme in adipocytes is conceivable that adipose tissue might be a source of serum ALP.
Est-3 carboxylesterase was not analyzed in this study, as a high level of polymorphism (61.7%) for a null Est-3 isozyme phenotype has been detected in four V.