isovaleryl-CoA


Also found in: Wikipedia.

i·so·va·ler·yl-CoA

(ī'sō-val'ĕr-il),
The condensation product of isovaleric acid and coenzyme A; an intermediate in the catabolism of l-leucine.
References in periodicals archive ?
Isovaleric academia (WA) is an autosomal recessive inborn error of leucine metabolism caused by a deficiency of isovaleryl-CoA dehydrogenase.
Patients with MMA do not have all of the features of isovaleric acidemia, including the characteristic odor of sweaty feet, which is related to isovaleryl-CoA accumulation.
Isovaleryl-CoA dehydrogenase activity in isovaleric acidemia fibroblasts using an improved tritium release assay.
Isovaleric acidemia (IVA) is an autosomal recessive genetic disorder of the enzyme isovaleryl-CoA dehydrogenase, which is involved in leucine metabolism (1).