isotype


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Related to isotype: idiotype, allotype

i·so·type

(ī'sō-tīp),
An antigenic determinant shared by all members of a class or subclass of an immunoglobulin molecule. Immunoglobulin isotypes include IgG, IgA, IgE, IgD, and IgM.
[iso- + G. typos, model]

isotype

(ī′sə-tīp′)
n.
1. A biological specimen or other element that is a duplicate of the holotype.
2. Any of the subclasses of immunoglobulins defined by the chemical and antigenic characteristics of their constant regions.

i′so·typ′ic (-tĭp′ĭk) adj.

i·so·type

(ī'sō-tīp)
An antigenic determinant (marker) that occurs in all members of a subclass of an immunoglobulin class.
[iso- + G. typos, model]
References in periodicals archive ?
However, it was recently observed that hepatic ANGPTL4 and PPARD (not PPARA) expression was upregulated during acute inflammation suggesting that in bovine this PPAR isotype also may regulate expression of the hepatokine [172].
Carrillo Puerto, selva mediana subperennifolia, 8 m elevacion, 9 April 1986, R Villanueva 714 (holotype: MEXU; isotypes: MO, XAL).
Cell populations were defined as positive for a particular CD marker if more than 20% of the leukemic blasts events were above isotype control threshold, otherwise they were defined negative.
Thereafter, sections were incubated with mouse anti-rat FR[beta] IgM (final concentration 1 [micro]g/ml) or isotype control IgM (ab35768, Abcam, Cambridge, UK; final concentration 1 [micro]g/ml) in 10% FBS/PBS for 24 hours at 4[degrees]C or with 10% FBS/PBS.
After incubation with a blocking solution containing 10% goat serum (v/v%, Gibco; CA) for 1 h, the cells were incubated with primary antibodies against tryptase or chymase or isotype control.
In spite of the prevalence of anti-dsDNA IgM and IgA isotypes in SLE, they are not routinely measured during the follow-up of these patients, and their diagnostic values in SLE are still a topic of considerable interest.
The isotype of antibodies elicited in cattle by the two dendrimers differs from those induced in swine [16].
(8) Salivary antibodies of the IgA isotype have been considered as biomarkers of infection, and also of immunity, considering that they may play a role in inhibiting cell adhesion and in opsonophagocytosis.
Type: Turkey, C5 Nigde: Camardi, 2 km South of Demirkazik village, subalpine community with dwarf shrub and thorn-cushion, 1760 m, limestone, 22 June 2015, 37[degrees]50'47"N, 35[degrees]05'32"E, Binzet 201501 (holotype: ANK; isotype: GAZI).
To do so, we treated lean wildtype (WT) and obese db/db mice with an ST2 blocking or isotype antibody prior to [O.sub.3] exposure.
reported the novel category of monoclonal IgG deposition disease characterized by membranoproliferative glomerulonephritis or endocapillary glomerulonephritis on light microscopic findings, staining for a single light-chain isotype and a single gamma heavy-chain subclass on immunofluorescence findings, and granular electron-dense deposits on electron microscopic findings [1].