isotretinoin


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isotretinoin

 [i″so-tret´ĭ-no-in]
a synthetic form of retinoic acid (13-cis-retinoic acid), used orally to clear cystic and conglobate acne.

i·so·tret·i·noin

(ī'sō-tret'i-noyn),
A retinoid used to treat severe recalcitrant cystic acne; a known human teratogen.

isotretinoin

(ī′sō-trĕt′n-oin′)
n.
A synthetic isomer of retinoic acid that inhibits sebaceous gland secretion and is used in the treatment of severe nodular acne. It can cause birth defects if taken during pregnancy.

isotretinoin

Retinoic acid, 13-cis retinoic acid A retinoid used to treat acne and psoriasis and may ↓ tumor development Side effects Inflammation of skin and mucosa, hepatitis

i·so·tret·i·no·in

(ī'sō-tret'i-nō'in)
A retinoid used to treat severe recalcitrant cystic acne; a known human teratogen.

isotretinoin

A RETINOID drug used to treat ACNE. The oral preparation is used under strictly controlled conditions to exclude pregnancy because of the known risks to the fetus. Brand names are Roaccutane, and, for external use Isotrex and Isotrexin.

Isotretinoin

A powerful vitamin A derivative used in the treatment of acne. It can promote scarring after skin resurfacing procedures.
Mentioned in: Acne, Skin Resurfacing

i·so·tret·i·no·in

(ī'sō-tret'i-nō'in)
A retinoid used to treat severe recalcitrant cystic acne; known human teratogen.
References in periodicals archive ?
A total of 17,829 psychiatric adverse events in which isotretinoin was the primary suspect drug were reported during the study period.
This study found that the number of pregnancies in women taking isotretinoin fell after the program was implemented, but there are still hundreds happening each year.
The Zenatane (Isotretinoin Capsules, USP) in 10 mg, 20 mg, 30 mg and 40 mg is reportedly the therapeutic equivalent generic version of Accutane and is being launched under an approved Risk Evaluation and Mitigation Strategy (REMS) Programme as well as the US FDA's special restricted iPLEDGE distribution programme.
The use of isotretinoin is fraught beyond the issue of teratogenicity; this is a patient population at higher risk for depression, and isotretinoin has been associated with affective impacts.
The patient was started systemic isotretinoin at 30 mg / day (0.5 mg/kg/d).
Isotretinoin is also used to treat various disorders such as rosacea, periorificial dermatitis, seborrheic dermatitis, folliculitis, granuloma annulare, sarcoidosis, and photoageing (7).
Louis, and his associates suggest that isotretinoin induces a "sebaceous drought," which shifts the skin microbiome from pathogenic to normophysiological.
Keywords: isotretinoin, pseudotumor cerebri, herpes simplex encephalitis, side effect.
Systemic isotretinoin is the best option when other treatments fail.
Retinoids include the active substances acitretin, adapalene, alitretinoin, bexarotene, isotretinoin, tazarotene and tretinoin.