isotonic saline

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Related to isotonic saline: hypotonic saline

isotonic saline

sterile sodium chloride solution at physiological concentration (0.87%); used as a wound-cleansing agent or irrigating fluid


1. of equal tension.
2. denoting a solution in which body cells can be bathed without net flow of water across the semipermeable cell membrane; also, denoting a solution having the same tonicity as another solution with which it is compared.

isotonic contraction
muscle contraction without appreciable change in the force of contraction; the distance between the muscle's origin and insertion becomes lessened.
isotonic dehydration
occurs when the fluid lost is isotonic with serum, as in sweating, simple enteritis, nephrosis. There are therefore no errors of electrolyte balance likely to result.
isotonic saline
see normal saline.
References in periodicals archive ?
Laryngeal Desiccation Challenge and Nebulized Isotonic Saline in Healthy Male Singers and Nonsingers: Effects on Acoustic, Aerodynamic, and Self-Perceived Effort and Dryness Measures," Journal of Voice (In press, corrected proof, 2015); DOI:10.
1mg/dL who underwent radiographic procedure requiring contrast media to receive isotonic saline or sodium bicarbonate at a similar rate of 3 mL/kg/h for 1 h before and 1mL/hg/h for 6h after the procedure.
After a tracheotomy (PE250, Portex, UK), a polyethylene catheter (PE50, Portex, UK) was inserted into the left jugular vein to enable the administration of an iv maintenance infusion of isotonic saline (0.
Prevention of hospitalacquired hyponatremia: A case for using isotonic saline.
Group P/S (n = 8) received the same treatment as described for the previous group, except 10 min before each N trial these rats were injected with isotonic saline (equal volume, i.
1 mg/dL were randomized to receive isotonic sodium bicarbonate (n = 60) or isotonic saline (n = 59) at a rate of 3 mL/kg/hour for 1 hour before and 1 mL/kg/hour for 6 hours after contrast administration.
The erythrocyte pellet was resuspended in isotonic saline and centrifuged again.
Giancarlo Marenzi and his coworkers at the University of Milan published a randomized trial that involved 92 patients with chronic kidney disease who were assigned to intravenous hydration with isotonic saline for 12 hours before and after iodinated contrast exposure (controls), 12 hours of intravenous hydration before contrast exposure followed by 18-24 hours of hemofiltration after, or hemofiltration for 6 hours before and again for 18-24 hours after, contrast exposure.
A group from Turkey recently published a comparison of 1 mL intraoperative isotonic saline irrigation, postoperative antibiotic treatment (sulbactam/ampicillin 25 mg/kg for 5 days), postoperative ofloxacin drops (twice a day for 5 days), or placebo in 280 children (mean age 5.