isothiocyanates


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isothiocyanates

Compounds plentiful in green cruciform vegetables such as broccoli and cabbage. Isothiocyanates are believed to be eliminated by glutathione-S-transferase, and in people negative for the genes of this enzyme these vegetables appear to offer substantial protection against lung cancer.
References in periodicals archive ?
Caption: Boost your diet with broccoli isothiocyanates for cancer protection.
Chung, "Isothiocyanates as cancer chemopreventive agents: their biological activities and metabolism in rodents and humans," Current Drug Metabolism, vol.
RESULTS: The isothiocyanates 6-methylsulfinylhexyl isothiocyanate (6-HITC) and sulforaphane (SFN) activated Nrf2 and up-regulated downstream proteins associated with MeHg excretion, such as glutamate-cysteine ligase, glutathione 5-transferase, and multidrug resistance--associated protein, in primary mouse hepatocytes.
Isothiocyanates can cause goiter and then the swelling of the thyroid may lead to the abnormal secretion of T3 and T4.
stenopetala seeds was dominated by isothiocyanates; benzyl isothiocyanate (54.30%) and isobutyl isothiocyanate (16.37%) were the major components.
In the multivariate analysis, results were adjusted for age, gender, dialect group, education level, number of cigarettes smoked per day, years of smoking, frequency of alcohol intake, intake of isothiocyanates, intake of Chinese-style preserved foods, body mass index, and parity in women.
The results were adjusted for potential confounders, including age at enrollment, year of enrollment, sex, dialect group, level of education, number of cigarettes smoked per day, number of years smoking, number of years since quitting smoking (for former smokers), and dietary intake of beta-cryptoxanthin and isothiocyanates.
These vegetables contain high levels of glucosinolates, which when eaten break down to release isothiocyanates. Evidence shows that these isothiocyanates are among the most powerful anti-cancer agents in the diet.
Additional chapters present new information about isothiocyanates, lycopene, carotenoids other than beta-carotene, tocotrienols, and phytoestrogens.
The cavity-fighting chemicals, called isothiocyanates, are also the source of wasabi's sharp smell and taste.
It could be their phytochemicals--things like carotenoids, vitamins C and E, selenium, indoles, isothiocyanates, flavonoids, phenols, and limonene.