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The radical of isothiocyanic acid, -N=C=S.
Farlex Partner Medical Dictionary © Farlex 2012


(ī″sō-thī″ō-sī′ă-nāt″) [″ + ″],


A member of a family of compounds found in some cruciferous vegetables, as well as horseradish and mustards. ITCs have cancer-preventing effects in animals.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Benzyl isothiocyanate (BITC) triggers mitochondria-mediated apoptotic machinery in human_cisplatin-resistant_ oral cancer CAR cells.
First, toxicologic testing did not find evidence of methyl isothiocyanate in the blood samples of the patients tested.
This effect has been attributed to compounds in PAP such as alkaloids carpaine and carpasemin or to cysteine proteases or benzyl isothiocyanate. Based on chromatographic quantification of these compounds and anthelmintic tests, benzyl isothiocyanate was reported to be the major source of the anthelmintic activity in papaya seeds [46].
Isshiki, "Effect of humidity on Allyl isothiocyanate antimicrobial activity," Nippon Shokuhin Kagaku Kogaku Kaishi, vol.
The resulting products can give glucose, and unstable aglycone and aglycone can be rearranged into isothiocyanates (ITCs), nitriles, and other products.
The presence of hexachlorocyclotriphosphazene in a one-pot reaction system is envisaged, not only forming isothiocyanate intermediate 2 via P-Cl substitution but also generating [Cl.sup.-] from the partially soluble KCl in acetone [31].
Takenaka, "Quantitation of a bioactive metabolite in undisturbed rhizosphere--Benzyl isothiocyanate from Carica papaya L.," Journal of Chemical Ecology, vol.
Cultured cells were washed with PBS and stained with fluorescein isothiocyanate (FITC)-labeled antihuman CD69 mAbs, R-phycoerythrin (PE)-labeled anti-human CD25 mAbs (IL-2 receptor) and allophycocyanin (APC)-labeled anti-human CD4 or CD8 mAbs for 15 min at 4[degrees]C (all antibodies were purchased from eBioscience).
Anuradha Sehrawat, Ph.D., will discuss how breast cancer stem cell growth is inhibited when a protein called Ron sensitizes the stem cells to the benzyl isothiocyanate molecule in cruciferous vegetables.
Inside the cell hydrolysis of glucosinolate by myrosinase enzyme (thioglucoside glucohydrolase) produces a spectrum of products which the most important of them is isothiocyanate. Recently, the biochemical and genetic studies performed on the Arabidospis plant confirm the existence of amino acid precursor in the glucosinolate biosynthesis pathway.
For synthesis of FISM, DBTDL was used to catalyze the reaction between FITC molecules with starch maleate molecules by activating isothiocyanate molecules of FITC.