methylmalonic acid

(redirected from isosuccinic acid)

methylmalonic acid

 [meth″il-mah-lon´ik]
a carboxylic acid that is a structural isomer of succinic acid; occurring in excess in the blood and other body fluids in methylmalonicacidemia.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

meth·yl·ma·lon·ic ac·id

(meth'il-mă-lon'ik as'id),
2-Methylpropanedioic acid, an important intermediate in fatty acid metabolism; seen in elevated levels in cases of vitamin B12 deficiency. Note that methylmalonate is not methyl malonate, which is the dimethyl ester of malonate.
Synonym(s): isosuccinic acid
Farlex Partner Medical Dictionary © Farlex 2012

methylmalonic acid

A dicarboxylic acid intermediate in fatty acid metabolism, and a C-methylated derivative of malonate, which is increased in vitamin B12 and/or folate deficiency.

Ref range
• Serum, MA, 80–300 nmol/L; homocysteine, 8–20 µmol/L.
• Urine, MA < 3.6 mmol/mol creatinine.

Specimen
Serum, random urine.
 
Method
GC/MS, HPLC
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

methylmalonic acid

Isosuccinic acid An intermediate in fatty acid metabolism, which is ↑ in vitamin B12 and/or folate deficiency
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.