isoretinoin

13-cis-retinoic acid A proprietary vitamin A analogue used to treat refractory acne, leukoplakia, and induce long-term clinical and lab remissions in juvenile CML Teratogenicity It is a category X drug–ie, teratogenic, contraindicated in pregnancy–causes cardiac malformations–VSD, aortic arch and conotruncal defects, external ear deformity, cleft palate, micrognathia, CNS malformations. See Vitamin A analogues.

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Isotretinoin (Nau, 2001) is one of the drugs that shows negligible effects in mouse and rat (Kochhar and Penner, 1987; Kamm, 1982), while in monkeys (Fantel et al., 1977) and (possibly) humans, isoretinoin can cause great disturbances of embryonic development.

Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use

(13) The most commonly prescribed teratogens in this study were topiramate, methotrexate, and isoretinoin. Among the specialists who prescribed the medications, dermatologists documented contraceptive counseling in 47% of visits--likely because of the federally mandated risk mitigation system for prescribing isoretinoin.

Can we solve the problem of inadequate contraception for women at high risk for adverse pregnancy outcomes?

Anti-GD2 antibody with GM-CSF interleukin-2, and isoretinoin for neuroblastoma.

Adult adrenal ganglioneuroblastoma: a rare case report

(15.) McGinn T, Bewira C: Isoretinoin (Accutane) associated pancolitis.

Does isotretinoin cause inflammatory bowel disease?/Isotretinoininflamatuvar barsak hastaligina yol aciyor mu?

Patients who used systemic antifungal or isoretinoin within 6 months of the first scheduled laser session were excluded.

The effect of Q-switched Nd:YAG 1064 nm/532 nm laser in the treatment of onychomycosis in vivo

Low dose isoretinoin is a well-tolerated method of chemoprevention although further research is needed to explore its efficacy (2,3).

Subcutaneous spreading squamous cell carcinoma in a patient with epidermolysis bullosa

Isoretinoin, marketed as Accutane in the US and Roaccutane in the UK, resolves acne in as many as 89% of patients.

Acne drug warning

A study has found Isoretinoin, marketed as Accutane in the US and Roaccutane in the UK, resolves acne in as many as 89% of patients.

Medicine risk

Your GP can refer you to a specialist who may prescribe a drug called isoretinoin if it is really bad, but this needs to be monitored by a dermatologist.

DOCTOR'S SURGERY; My son's in agony, but can't see doc for months

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