isoretinoin

isoretinoin

13-cis-retinoic acid A proprietary vitamin A analogue used to treat refractory acne, leukoplakia, and induce long-term clinical and lab remissions in juvenile CML Teratogenicity It is a category X drug–ie, teratogenic, contraindicated in pregnancy–causes cardiac malformations–VSD, aortic arch and conotruncal defects, external ear deformity, cleft palate, micrognathia, CNS malformations. See Vitamin A analogues.
References in periodicals archive ?
Isotretinoin (Nau, 2001) is one of the drugs that shows negligible effects in mouse and rat (Kochhar and Penner, 1987; Kamm, 1982), while in monkeys (Fantel et al., 1977) and (possibly) humans, isoretinoin can cause great disturbances of embryonic development.
(13) The most commonly prescribed teratogens in this study were topiramate, methotrexate, and isoretinoin. Among the specialists who prescribed the medications, dermatologists documented contraceptive counseling in 47% of visits--likely because of the federally mandated risk mitigation system for prescribing isoretinoin.
Anti-GD2 antibody with GM-CSF interleukin-2, and isoretinoin for neuroblastoma.
Patients who used systemic antifungal or isoretinoin within 6 months of the first scheduled laser session were excluded.
Low dose isoretinoin is a well-tolerated method of chemoprevention although further research is needed to explore its efficacy (2,3).
Isoretinoin, marketed as Accutane in the US and Roaccutane in the UK, resolves acne in as many as 89% of patients.
A study has found Isoretinoin, marketed as Accutane in the US and Roaccutane in the UK, resolves acne in as many as 89% of patients.
Your GP can refer you to a specialist who may prescribe a drug called isoretinoin if it is really bad, but this needs to be monitored by a dermatologist.