isoprenaline


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Related to isoprenaline: propranolol, atropine

i·so·pro·te·re·nol

(ī'sō-prō-ter'ĕ-nol),
A sympathomimetic β-receptor stimulant possessing the cardiac excitatory, but not the vasoconstrictor, actions of epinephrine. Chemically it differs from epinephrine in having an isopropyl group replacing the methyl group attached to the nitrogen atom; rarely used because of the availability of more specific agents.

isoprenaline

An ADRENALINE - like drug given by injection to treat surgical SHOCK and HEART BLOCK. The drug is on the WHO official list. A brand name is Saventrine.
References in periodicals archive ?
Isoprenaline (ISO), a [beta]-adrenoceptor agonist, is one of synthetic catecholamine and has been reported to causes severe oxidative stress in the myocardium, resulting in infarct-like necrosis of the heart muscle.
Effect of isoprenaline on the expression of vascular endothelial growth factor and cell viability in human umbilical vein endothelial cells
In the study of Lin Chang; none of the rats in Control (C) group, Ghrelin (G) group and Isoprenaline + Ghrelin in high dose (ISO + GH) group died during the experimental period.
A well known example of non-classical bioisosteric replacement have been reported for the hydroxyl group as shown in case of bronchodilator isoprenaline (isoproterenol) in which 3-OH group replacement with other bioisosteric group like 3- CH 2 OH, resulting salbutamol (albuterol), selective beta-2 agonist, a well known anti-asthamatic drug, by 3-NHSO 2 CH 3 , resulting soterenol and by 3- NHCONH 2 , resulting carbuterol [42-43].
Adeniran et al., "Modeling the chronotropic effect of isoprenaline on rabbit sinoatrial node," Frontiers in Physiology, vol.
Busse, "Effect of Bordetella pertussis vaccination in mice and the isolated tracheal response to isoprenaline," Allergy, vol.
Newsholme, "Effects of the [beta]-adrenoceptor agonist isoprenaline on insulin-sensitivity in soleus muscle of the rat," Biochemical Journal, vol.
The procedure was considered successful when post ablation tachycardia could not be induced within two minutes of isoprenaline 2ug/ minute with infusion pump.
An epidemic of asthma deaths in a number of countries, including New Zealand and Australia, but not the United States (US), occurred with the introduction of isoprenaline forte in the 1960s.
However, SH rats have greater increases in BP in response to adrenalin (Yamaguchi and Kopin 1980) and proportional increases in BP in response to isoprenaline (Weinstock and McCarthy 1983) compared with WKY rats and hence might have had a higher peak BP response than WKY rats during dobutamine administration despite the preexisting hypertension.
Type 2 Diarrhea Depression Diabetes Malaria Codeine Citalopram Repaglinide Atovaquone Phosphate Diphenoxylate Duloxetine Acarbose Sulfadoxine Steroid Budesonide Serotonin Metformin Pyrimethamine Reuptake Inhibitors Loperamide Repaglinide Artemether & Lumefantrine Metformin Amodiaquine Proguanil Malaron Atovaquone & Proguanil Diarrhea Diabetes Asthma Hypertension Codeine Glyburide Beclomethasone Propranolol Phosphate Dipropionate Diphenoxylate Intensive Ipratropium Angiotensin insulin Bromide Steroid Budesonide Enalapril Aminophylline Chlorthalidone Loperamide Insulin Isoprenaline Nisoldipine Repaglinide Salbutamol Hyperglycemia Angiotensin Hyperglycemia & Insulin [FIGURE 3 OMITTED]