isopeptide bond

Also found in: Wikipedia.

i·so·pep·tide bond

an amide linkage between a carboxyl group of one amino acid and an amino group of another amino acid in which at least one of these groups is not on the α-carbon of one of the amino acids; for example, the bond between the glutamyl residue and the cysteinyl residue of glutathione. Compare: peptide bond, eupeptide bond.
References in periodicals archive ?
We have designed a unique way to connect protein building blocks irreversibly and precisely, via spontaneous isopeptide bond formation.
Epsilon]]([Gamma]-glutamyl) lysine isopeptide bond between the [Gamma]-amide sidechain of a donor glutamine residue and the [Epsilon]-N[H.
He noted that aging slows ubiquitin-proteasome proteolytic activity, resulting in the accumulation of ubiquitinylated proteins via isopeptide bonds.
As you may know, transglutaminase is a transferase that forms isopeptide bonds between lysyl and glutaminyl residues.