The acyl radical of isoleucine.
Farlex Partner Medical Dictionary © Farlex 2012
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The most common is Jo-1 (histidyl) (15%-30% prevalence), followed by PL-7 (threonyl) and PL-12 (alanyl), with a prevalence of 5% to 10%, followed by EJ (glycyl), OJ (isoleucyl), KS (asparaginyl), Zo (phenylalanyl), and YRS (tyrosyl) (all with prevalences of 1%-5%).
Furthermore, this important activity of wide range of mushrooms could be attributed to their isolated bioactive hypotensive compounds, for instance, isoleucyl tyrosine (dipeptide) from M.
MRSA, methicillin-resistant Staphylococcus aureus; ST, sequence type; SCC, staphylococcal cassette chromosome; spa, staphylococcal protein A; PFGE, pulsed-field gel electrophoresis; HA, healthcare-associated; Chl, chloramphenicol; Ery, erythromycin; Gen, gentamicin, Mup, mupirocin; acA-aphD, aminoglycoside resistance gene encoding the bifunctional enzyme, 6'-aminoglycoside N-acetyltransferase/2"-aminoglycoside phosphotransferase; ermC, gene encoding macrolide-lincosamide-streptogramin B resistance; ileS-2, gene encoding high-level mupirocin resistance mediated by isoleucyl tRNA-synthetase; CA, community-associated.
It is a tiny molecule that binds to fungal isoleucyl transfer RNA, thus affecting a wide range of Candida species.
In comparison, the isoleucyl tRNA synthetase can only discriminate at a level of one to two hundred, but then uses the full power of a protein to edit out valine.