isoimmunization


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isoimmunization

 [i″so-im″u-nĭ-za´shun]
development of antibodies in response to isoantigens.

i·so·im·mu·ni·za·tion

(ī'sō-im'yū-nī-zā'shŭn),
Development of a significant titer of specific antibody as a result of antigenic stimulation with material contained on or in the red blood cells of another individual of the same species; for example, isoimmunization is likely to occur when an Rh-negative person is treated with a transfusion of Rh-positive blood from another human being, or an Rh-negative woman has a pregnancy in which the fetus inherits Rh-positive red blood cells.

i·so·im·mu·ni·za·tion

(ī'sō-im'yū-nī-zā'shŭn)
Development of a significant titer of specific antibody as a result of antigenic stimulation with material contained on or in the red blood cells of another individual of the same species.
References in periodicals archive ?
Burnham, "Isoimmunization in pregnancy: its possible bearing on the etiology of erythroblastosis foetalis," Journal of the American Medical Association, vol.
Herein we describe a preterm neonate with hydrops fetalis due to Kell isoimmunization that was detected during the postnatal period, and discuss the perinatal approach to this rare condition.
The study included 111 fetuses at risk for hemolytic disease of the newborn due to red cell isoimmunization, and 265 healthy fetuses.
Failure of ultrasonographic parameters to predict the severity of fetal anemia in rhesus isoimmunization. Am J Obstet Gynecol 1988;158:920-926.
"Kernicterus" was originally a term describing the typical autopsy findings of the brain in infants who died during severe jaundice, often caused by Rh isoimmunization or by infection.
The 5200 practice questions in this study aid are divided into 62 chapters on such pregnancy problems as breech, hypertension, fetal abnormalities, Rh isoimmunization, and lactation, and on disorders uniquely affecting the female reproductive system.
Additionally, during this time, infants may have incurred additional Hg exposure through breast milk if they were born to mothers with Hg amalgam fillings and/or Rh-negative mothers, since many Rho(D)-immune globulin formulations, used to prevent isoimmunization in the Rho(D) negative individual exposed to Rho(D) positive foetal blood, contained thimerosal (10.5 to > 50 [micro]g Hg/ dose) and were routinely recommended for administration to these mothers within 72 h of birth (12, 13).
[30.] Isoimmunization. In: Concise medical dictionary [Internet].
Other causes include isoimmunization, placental abruption, maternal chronic diseases such as diabetes and hypertension, umbilical cord accidents (Cnattingius and Stephansson 2002; Simpson 2002), and maternal risk factors such as smoking (Wu et al.
Hemolytic anemia due to Rh isoimmunization is frequently Coombs' positive.
Modern methods for diagnosing and treating Rh isoimmunization have also made a dramatic difference in fetal death rates.