isoimmunization


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isoimmunization

 [i″so-im″u-nĭ-za´shun]
development of antibodies in response to isoantigens.

i·so·im·mu·ni·za·tion

(ī'sō-im'yū-nī-zā'shŭn),
Development of a significant titer of specific antibody as a result of antigenic stimulation with material contained on or in the red blood cells of another individual of the same species; for example, isoimmunization is likely to occur when an Rh-negative person is treated with a transfusion of Rh-positive blood from another human being, or an Rh-negative woman has a pregnancy in which the fetus inherits Rh-positive red blood cells.

isoimmunization

/iso·im·mu·ni·za·tion/ (-im″u-nĭ-za´shun) development of antibodies in response to isoantigens.

isoimmunization

[ī′sō·im′yənīzā′shən]
the development of antibodies against antigens from the same species, such as anti-Rh antibodies in an Rh-negative person. See also erythroblastosis fetalis.

i·so·im·mu·ni·za·tion

(ī'sō-im'yū-nī-zā'shŭn)
Development of a significant titer of specific antibody as a result of antigenic stimulation with material contained on or in the red blood cells of another individual of the same species.

isoimmunization

alloimmunization.

isoimmunization of pregnancy
see alloimmunization of pregnancy.
References in periodicals archive ?
The patient's Kell antigen was positive, his mother's was negative, and the maternal serum indirect Coombs test was positive; therefore, the diagnosis of Kell isoimmunization was confirmed.
These include concentration of unconjugated bilirubin high enough to exceed the bilirubin-binding capacity of albumin, due to severe hemolysis from Rh isoimmunization (18); bilirubin displacement from albumin by competing or affinity-altering molecules such as sulfisoxazole (19) or free fatty acids (20); and disruptions of the blood-brain barrier that allow bilirubin-protein complexes to enter the brain.
Rho(D)-immune globulin is used to prevent isoimmunization in the Rho(D) negative individual exposed to Rho(D) positive blood.
Scheininger acknowledged that he did not diagnose his patient's Rh isoimmunization during the 1984 pregnancy, and that his failure to treat her for that condition was a factor that resulted in the stillbirth of an infant boy named Brian.
TABLE 1 Conditions Often Evaluated by the Nonstress Test * Decreased fetal movement * Diabetes * Oligohydramnios * Sonographic evidence of intrauterine growth retardation * Hypertensive disorders * Postterm pregnancy * Isoimmunization * Renal disease * Autoimmune diseases, especially lupus * Maternal cyanotic heart disease * Previous unexplained fetal demise * Hemoglobinopathies * Multiple gestation with discordant growth * Hyperthyroidism
58) Furthermore, rhesus negative women who do not return for the prostaglandin and an anti-D immunoglobulin injection are at risk for rhesus isoimmunization and its associated complications in subsequent pregnancies.
Pham et al (1) raise an extremely important point about adjusting the dose of rhesus immunoglobulin to suppress isoimmunization during pregnancy in obese patients.
Suspected IUGR, absence of fetal well--being, Post term pregnancy, Isoimmunization.
Tenders are invited for Supply Drugs for Hiv-Aids Program and the National Program for Prevention of Rh Isoimmunization Syndrome
We define pre-existing conditions as malpresentation, genital herpes simplex virus, diabetes mellitus/abnormal glucose tolerance, hypertensive disorder, oligohydramnios, congenital/acquired abnormality of vagina, other congeuital/acquired anomaly, and rhesus (anti-D) isoimmunization.
Intraperitoneal transfusion in severe, early-onset Rh isoimmunization.