Fetal magnetocardiography (fMCG) to monitor cardiac time intervals in fetuses at risk for
isoimmune AV block.
2] Quickly rising or high bilirubin levels or marked jaundice developing within 24 hours after birth warrant investigation of causative pathology such as
isoimmune haemolysis (ABO and Rh incompatibility, congenital haemolytic disease) or bile duct disorders.
Passi GR, Kriplani A, Pati HP Choudhry VP
Isoimmune hemolysis in an infant due to maternal Evans' syndrome.
It is worrying to note that six (23%) of the babies readmitted for ET had
isoimmune haemolysis, suggesting that this condition was overlooked at birth.
Isoimmune neonatal neutropenia in a North African newborn due to anti-Fc[gamma] RIIIb.
Although the incidence of
isoimmune hydrops fetalis has decreased markedly, nonimmune hydrops fetalis cases have been more frequently reported.
Intravenous immunoglobulin in treatment of neonatal
isoimmune thrombocytopenia.
The systematic review completed by Alcock and Liley in 2002 [29] evaluates whether IVIG is effective in reducing the need for exchange transfusion in neonates with
isoimmune hemolytic jaundice ("
isoimmune," also "alloimmune," refers to the development of antibodies in an individual against antibodies from another individual in the same species [30], a broad group of diseases to which ABO incompatibility belongs).
Pregnancy history includes gestational age, maternal blood type, and Rh and
isoimmune antibody titers.
Unusual patterns of newborn jaundice, especially jaundice within the first day after delivery, should result in prompt follow-up investigations of prenatal maternal testing for ABO or unusual
isoimmune antibodies.
Maternal prenatal testing of ABO and Rh(D) typing and a serum screen for unusual
isoimmune antibodies should be reviewed if available.
