isoform


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isoform

One of two or more proteins coded independently by different genes, which have identical or nearly identical structures and functions.
References in periodicals archive ?
VEGF-A165b is an endogenous neuroprotective splice isoform of vascular endothelial growth factor A in vivo and in vitro .
The findings indicated that only one specific isoform of HSD17B4--isoform 2--enzymatically inactivated androgens and prevented tumor growth.
sup][9] According to our previous reports, the localization pattern of proteins expressed by the short isoform was different from the other two isoforms.
MetaStat is developing therapeutic product candidates and paired companion diagnostics based on a novel approach that makes the Mena isoform protein a drugable target.
The isoform e3e3 observed more than 70% in both groups which is more common and is considered as wild type.
In present study heterozygous AB BLG protein isoform significantly associated with whey protein contents in both goat breeds (pless than 0.
3 The HIAP isoform of IAP is secreted in fasting only in the secretor's blood group, while NIAP isoform is secreted in both secretors and non-secretors after taking fatty meals.
Moreover, we briefly discuss the therapeutic potential of direct and indirect inhibition of TF activity and/or isoform expression for cancer treatment.
The 5th isoform with high inhibitory activity (132 units) and trypsin-like proteinases low activity (0.
The presence of the MCT1 isoform in the plasma membranes of the fiber type I (oxidative trait) was identified in rats while the MCT4 isoform was found in a high percentage of type IIx fibers (glycolytic characteristic).
The investigation of VEGF isoform regulation might be the key for controlling and targeting the angiogenesis balance in pathologies, and also provides a link between angiogenesis, treatment of pathologies and the alternative splicing process(8), (9) In this article, the importance of VEGF alternative splicing process was evaluated in physiological and pathological situations.