isoflavone


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to isoflavone: Soy isoflavones

isoflavone

(ī′sō-flā′vōn′)
n.
1. A crystalline compound, C15H10O2, that is an isomer of flavone.
2. Any of a class of flavonoid phytoestrogens that are found primarily in soybeans and act as antioxidants.

isoflavone

Alternative pharmacology
Any of a number of hormone-like substances found in peanuts, beans and lentils, which are thought to have anticarcinogenic properties.

isoflavone

Nutrition Any of a family–eg, genistein, daidzen, of phytoestrogens in peanuts, beans, soy beans, lentils, that are carcinoprotective and ↓ ASHD. Cf Genistein, Nutraceutical, Soy, Textured vegetable protein.
References in periodicals archive ?
Yoshida, "Inhibitory effects of a major soy isoflavone, genistein, on human DNA topoisomerase II activity and cancer cell proliferation," International Journal of Oncology, vol.
Anecdotal evidence suggests beneficial effects of soy isoflavones on PMS management because of their influence on endogenous oestrogen and actions on specific tissues.
There is growing interest in using soy isoflavones in diseases related to metabolic syndrome.
Isoflavone supplements stimulated the production of serum equol and decreased the serum dihydrotestosterone levels in healthy male volunteers.
Soy isoflavone supplementation 160 mg/day for 4 weeks in women with AV would lead to a significant reduction in the number of lesions AV.
The cells treated with isoflavone were larger than the cells in the control or [MPP.sup.+] group, and most isoflavone-treated cells had neuritis (Figure 2).
Hence, the aim of this study was to examine the probable effects of soy isoflavone extract on the tumor volume, diet consumption and survival rate of classic chemotherapeutic reagent docetaxel on mouse 4T1 breast tumor model.
The findings are from the dual-site, double-blind, placebo-controlled Soy Isoflavones for Reducing Bone Loss (SIRBL) study of women randomly assigned to placebo, or either 80 mg or 120 mg of daily soy isoflavones.
For instance, the Women's Isoflavone Soy Health (WISH) trial gave 325 healthy postmenopausal women 25 grams a day of either soy protein (with 91 milligrams of isoflavones) or milk protein for three years.
This profile of isoflavone constituents could be attributed to the conversion of malonyl-derivates into free glycosides or may be also the result from increased synthesis.
Daily doses of the supplement containing 10, 20 or 40 mg of S-equol each reduced the frequency of moderate to severe hot flashes similarly to a 50 mg dose of a soy isoflavone supplement in a double-blinded randomised study involving 102 US postmenopausal women aged 45 to 65 who experienced more than 35 hot flashes weekly when they enrolled.