Yoshida, "Inhibitory effects of a major soy
isoflavone, genistein, on human DNA topoisomerase II activity and cancer cell proliferation," International Journal of Oncology, vol.
Anecdotal evidence suggests beneficial effects of soy
isoflavones on PMS management because of their influence on endogenous oestrogen and actions on specific tissues.
There is growing interest in using soy
isoflavones in diseases related to metabolic syndrome.
Isoflavone supplements stimulated the production of serum equol and decreased the serum dihydrotestosterone levels in healthy male volunteers.
Soy
isoflavone supplementation 160 mg/day for 4 weeks in women with AV would lead to a significant reduction in the number of lesions AV.
The cells treated with
isoflavone were larger than the cells in the control or [MPP.sup.+] group, and most isoflavone-treated cells had neuritis (Figure 2).
Hence, the aim of this study was to examine the probable effects of soy
isoflavone extract on the tumor volume, diet consumption and survival rate of classic chemotherapeutic reagent docetaxel on mouse 4T1 breast tumor model.
The findings are from the dual-site, double-blind, placebo-controlled Soy
Isoflavones for Reducing Bone Loss (SIRBL) study of women randomly assigned to placebo, or either 80 mg or 120 mg of daily soy
isoflavones.
For instance, the Women's
Isoflavone Soy Health (WISH) trial gave 325 healthy postmenopausal women 25 grams a day of either soy protein (with 91 milligrams of
isoflavones) or milk protein for three years.
This profile of
isoflavone constituents could be attributed to the conversion of malonyl-derivates into free glycosides or may be also the result from increased synthesis.
Daily doses of the supplement containing 10, 20 or 40 mg of S-equol each reduced the frequency of moderate to severe hot flashes similarly to a 50 mg dose of a soy
isoflavone supplement in a double-blinded randomised study involving 102 US postmenopausal women aged 45 to 65 who experienced more than 35 hot flashes weekly when they enrolled.
Irrigation level affects
isoflavone concentration of early maturing soya bean cultivars.