isoenzyme


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Related to isoenzyme: isoenzyme electrophoresis

isoenzyme

 [i″so-en´zīm]
any of several forms of an enzyme that all catalyze the same reaction but may differ in reaction rate, inhibition by various substances, electrophoretic mobility, or immunologic properties. Several enzymes, particularly alkaline phosphatase, lactate dehydrogenase, and creatine kinase, have clinically important isoenzymes. Isoenzymes are separated by electrophoresis, and the pattern indicates which damaged organ has released the enzymes.

i·so·en·zyme

(ī'sō-en'zīm),
An enzyme (one of a group) that catalyze the same reaction but may be differentiated by variations in physical properties, such as isoelectric point, electrophoretic mobility, kinetic parameters, or modes of regulation, for example, lactate dehydrogenase, a tetramer composed of varying amounts of α and β subunits (that is, 4α, 3α + 1β, 2α + 2β, 1α + 3β, and 4β).
Synonym(s): isozyme

isoenzyme

(ī′sō-ĕn′zīm′)
n.
An isoform that is an enzyme.

i′so·en·zy′mic adj.

i·so·en·zyme

(ī'sō-en'zīm)
One of a group of enzymes that catalyze the same reaction but may be differentiated by variations in physical properties, such as isoelectric point, electrophoretic mobility, kinetic parameters, or modes of regulation.

isoenzyme (isozyme)

one of a number of ENZYMES that catalyse the same reaction, but are qualitatively different from each other, for example in PRIMARY STRUCTURE.

Isoenzyme

One of a group of enzymes that catalyze the same reaction but are differentiated by variations in physical properties.
References in periodicals archive ?
Lactic dehydrogenase isoenzyme electrophoretic patterns in the diagnosis of pleural effusion.
In healthy adults, the greatest part of serum ALP levels is constituted from liver and bone isoenzymes, whereas the majority of serum ALP is bone-derived in children as a result of growth.
Wasilewska, "Pediatric reference data on activity of urinary N-acetyl-[beta]-D-hexosaminidase and its isoenzymes," Advances in Medical Sciences, vol.
Malate dehydrogenase (MDH) isoenzyme profiles of hybrid Shaktiman-1, Shaktiman-2 and their parents*.
Immunoenzymometric assay of human glycogen phosphorylase isoenzyme BB in diagnosis of ischemic myocardial injury.
In addition to increased absorption, piperine seems to be a non-specific general inhibitor of CYP isoenzymes; IV phenytoin levels also were higher among test participants.
The objective of this study was to determine the levels of serum LD2 isoenzyme and b2m in patients of NHL and to correlate these levels in NHL patients with and without bone marrow infiltration.
Electrophoresis was conducted at the same voltage as esterase isoenzyme electrophoresis, and the gel was stained using the method described in the study by Li et al.
Identification of isoenzyme C as the principal carbonic anhydrase in human ciliary processes.
Aspirin however acetylates also the COX-2 isoenzyme but due to slight sequence variations this evidently consumes less binding energy for arachidonic acid to become bound and be further metabolized [5].
PB is a hypnotic drug causing sleep in animals when administered, PB induced CP and its related isoenzyme, which in turn metabolize the drug causing sleep in the animal.
On the other hand it has been shown that using the various ADA isoenzymes and the isoenzyme ratio can be effective in the segregation of different reasons of increasing ADA in body fluids.