AP/LAT views of isodose
curves showed that absorbed dose at target point was slightly different for both applicators but there was no statistically significant difference noted (Figure-1)
We used Spearman correlation coefficients to clarify the correlation between the observed pain reduction effect and other related factors, such as the dose, prescribed isodose
lines, tumor percentage covered, and the difference in tumor volume before and after radiosurgery.
The median marginal dose to the MBTs was 16Gy (range 7-22), maximum dose to the MBTs was 32Gy (range 14-44), and the median 50% isodose
line was 50% (range 40-70).
5-cm thickness was used on the surface of the lesion to provide build up so to achieve the 100% isodose
line at the surface of the tumor.
He therefore underwent treatment with single-dose stereotactic irradiation delivered by a linear accelerator with 1,200 cGy prescribed to the 90% isodose
Three-dimensional imaging also has been applied to radiation therapy, especially to reconstruct isodose
surfaces and display them in conjunction with anatomical surfaces.
CORVUS with ActiveRx allows clinicians to 'draw' isodose
lines directly on CT scans, interactively 'push' dose out of sensitive structures, and 'click and drag' to adjust dose to planning volumes.
The dose was prescribed to the 60-85% isodose
line enclosing 100% of the GTV and more than 95% of the PTV.
Within 3 days prior to the start of radiation therapy, the hospital and referring physician must have localization films of right and left laterals, portal films of right and left laterals, Polaroid pictures of the patient in the treatment position with fields appropriately marked, the radiation therapy initial report form, any dose calculation worksheets and appropriate isodose
distribution and reference point calculations.
This is a very exciting program as we are able to not only fuse MRI and nuclear SPECT data to characterize drug distribution, but also to generate isodose
curves for an interstitially delivered radioimmunotherapy," commented Wessels.