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A cross-linking amino acid formed from lysyl residues; found in elastin.
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The crosslinking in elastin occurs by two polyfunctional amino acids, that is, desmosine and isodesmosine. They are formed by oxidative deamination of three out of every four lysine side chains.
[11]confirmedthe results and identified two components desmosine and isodesmosine acting as cross-link in ligament protein.
"The primary composition of this matrix is a natural ratio of complex proteins including glycosaminoglycans, collagen, elastin, desmosine, isodesmosine and transforming growth factor." For more information: