isocarboxazid


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Related to isocarboxazid: Linezolid, Selegiline, tranylcypromine

isocarboxazid

 [i″so-kahr-bok´sah-zid]
a monoamine oxidase inhibitor administered orally as an antidepressant and in the prevention of migraine.

isocarboxazid

/iso·car·box·a·zid/ (i″so-kahr-bok´sah-zid) a monoamine oxidase inhibitor used as an antidepressant and in the prophylaxis of migraine.

isocarboxazid

(ī′sō-kär-bŏk′sə-zĭd)
n.
A monoamine oxidase inhibitor, C12H13N3O2, used as an antidepressant.

isocarboxazid

[-kärbok′səzid]
a monoamine oxidase inhibitor.
indication It is prescribed in the treatment of mental depression.
contraindications Liver or kidney dysfunction; congestive heart failure; pheochromocytoma; concomitant use of a sympathomimetic drug or foods high in tryptophan, tyramine, or caffeine; or known hypersensitivity to the drug prohibits its use. Must be used with caution in patients with suicidal ideation.
adverse effects Among the more serious adverse effects are hyperactivity, cardiac arrhythmia, hypotension, vertigo, dryness of mouth, constipation, and blurred vision. Monoamine oxidase inhibitors produce many adverse drug interactions.

isocarboxazid

A monoamine oxidase inhibitor (MAOI) antidepressant drug.
References in periodicals archive ?
Isocarboxazid was started at 20 mg/day and increased as needed and tolerated to a maximum of 60 mg/day.
In this trial, isocarboxazid showed very robust clinical efficacy in the prophylactic treatment of migraine attack," Dr.
Tyramine-containing foods plus furazolidone, isocarboxazid, phenelzine, selegiline, or tranylcypromine: May cause dangerously high blood pressure.
These drugs include phenelzine, isocarboxazid, and tranylcypromine.
32-36) Isocarboxazid should not be used in patients with severe renal impairment, according to the prescribing information.
isocarboxazid (Marplan) phenelzine (Nardil) selegiline (Carbex, Eldepryl) tranylcypromine (Pamate) Other Medications bisacodyl (Dulcolax) Stimulant laxative.
11) The manic switch has occurred, however, after use of isocarboxazid, (8) trazodone, (12) and, in this case, phenelzine, which have only mild anticholinergic activity.
Rothschild AJ: Mania after withdrawal of isocarboxazid.
Four MAOIs are available in the United States: tranylcypromine, phenelzine, isocarboxazid, and selegiline.
John's wort), imipramine, MDMA, meperidine, nefazodone, nortriptyline, paroxetine, protriptyline, sertraline, tramadol, trazodone, venlafaxine Drugs that decrease Isocarboxazid, linezolid, phenelzine, 5-HT metabolism selegiline, tranylcypromine Drugs that are direct Almotriptan, buspirone, dihydroergotamine, 5-HT agonists eletriptan, frovatriptan, LSD, naratriptan, rizatriptan, sumatriptan, zolmitriptan Others L-tryptophan, carbamazepine, carisoprodol, droperidol, levodopa, lithium, metoclopramide, pentazocine, phenylpropanolamine 5-HT: serotonin; LSD: lysergic acid; MDMA: methylenedioxymethamphetamine Source: Reference 1