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isocarboxazid/iso·car·box·a·zid/ (i″so-kahr-bok´sah-zid) a monoamine oxidase inhibitor used as an antidepressant and in the prophylaxis of migraine.
A monoamine oxidase inhibitor, C12H13N3O2, used as an antidepressant.
a monoamine oxidase inhibitor.
indication It is prescribed in the treatment of mental depression.
contraindications Liver or kidney dysfunction; congestive heart failure; pheochromocytoma; concomitant use of a sympathomimetic drug or foods high in tryptophan, tyramine, or caffeine; or known hypersensitivity to the drug prohibits its use. Must be used with caution in patients with suicidal ideation.
adverse effects Among the more serious adverse effects are hyperactivity, cardiac arrhythmia, hypotension, vertigo, dryness of mouth, constipation, and blurred vision. Monoamine oxidase inhibitors produce many adverse drug interactions.