islets of Langerhans


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Related to islets of Langerhans: insulin, pancreas, somatostatin

is·lets of Lan·ger·hans

(lahng'ĕr-hahnz),
cellular masses consisting of several to several hundred cells lying in the interstitial tissue of the pancreas; they are composed of five different cell types that make up the endocrine portion of the pancreas and are the sources of insulin, glucagon, somatostatin, pancreatic polypeptide, and gastrin.

islets of Langerhans

(ī′lĭts; läng′ər-häns′)
pl.n.
Irregular clusters of endocrine cells scattered throughout the tissue of the pancreas that secrete insulin and glucagon. Also called islands of Langerhans.

is·lets of Lan·ger·hans

(ī'lĕts lahng'er-hahnz)
Cellular masses varying from a few to hundreds of cells lying in the interstitial tissue of the pancreas; they are the source of insulin and glucagon.

Islets of Langerhans

INSULIN secreting collections of cells lying in the INTERSTITIAL tissue of the PANCREAS. (Paul Langerhans, 1847–1888, German medical student, later anatomy professor).

islets of Langerhans

groups of cells found scattered in the pancreas of jawed vertebrates.

Islets of Langerhans

Special structures in the pancreas responsible for insulin secretion among other functions. They are named for Paul Langerhans, the German researcher who first identified them in 1869.

Langerhans,

Paul, German anatomist, 1847-1888.
islets of Langerhans - cellular masses composed of different cell types that comprise the endocrine portion of the pancreas and are the source of insulin and glucagon. Synonym(s): islet tissue; Langerhans islands; pancreatic islands; pancreatic islets
Langerhans cell granulomatosis
Langerhans cells - dendritic clear cells in the epidermis that are active participants in cutaneous delayed hypersensitivity.
Langerhans granule - a small membrane-bound granule first reported in Langerhans cells of the epidermis. Synonym(s): Birbeck granule
Langerhans islands - Synonym(s): islets of Langerhans

is·lets of Lan·ger·hans

(ī'lĕts lahng'er-hahnz)
Cellular masses consisting of several to several hundred cells lying in interstitial pancreatic tissue.
References in periodicals archive ?
Caption: Figure 4: The islets of Langerhans (a), red arrow and regenerated islet cells (b), encircled in the tissue sections of the pancreas of diabetic rat treated with the root extract of Uvaria chamae (100mg/kg) (H&E; (a) x100; (b) x400).
The objective of this study was to see the effects of sodium cyclamate on islets of langerhans. It has been proposed that artificial sweeteners affect the glucose metabolism of the body as well as insulin secretion.
sylvaticus lead to a decrease in blood sugar levels in diabetic animals, with intermediate values regarding the area of the islets of Langerhans and number of nuclei between untreated diabetic animals and controls.
The endocrine role of the pancreas in metabolism, and indeed the existence of insulin, was not further clarified until 1921, when Sir Frederick Grant Banting and Charles Herbert Best repeated the work of Von Mering and Minkowski, and went further to demonstrate they could reverse induced diabetes in dogs by giving them an extract from the pancreatic islets of Langerhans of healthy dogs.
Now, however, researchers have found a new way to study the insulin-producing beta-cells: by transferring the Islets of Langerhans to the eye.
sylvestre stimulated the insulin secretion in islets of Langerhans and pancreatic [beta]-cell lines (Persaud et al., 1999).
Pancreatic islets of Langerhans from 6-month-old [F.sub.1] mice were isolated by collagenase (Sigma) digestion as previously described (Alonso-Magdalena et al.
Furthermore, the [alpha]-gal antigen expression is not ubiquitously present in all porcine cell types, and in particular it is not expressed on the beta cells of the islets of Langerhans (Vales-Gonzalez et al., 2005).
38 The islets of Langerhans, involved in the production of insulin, are found in which organ?
Embedded within the exocrine tissue are countless (perhaps millions of) cells called the islets of Langerhans, which Dr.
Insulin is a hormone produced by the pancreas, an organ near the stomach, in small glands called the Islets of Langerhans. Insulin is responsible for pulling glucose that is circulating in the blood into the cells of the body to be used as energy.