islets of Langerhans

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is·lets of Lan·ger·hans

(lahng'ĕr-hahnz),
cellular masses consisting of several to several hundred cells lying in the interstitial tissue of the pancreas; they are composed of five different cell types that make up the endocrine portion of the pancreas and are the sources of insulin, glucagon, somatostatin, pancreatic polypeptide, and gastrin.

islets of Langerhans

(ī′lĭts; läng′ər-häns′)
pl.n.
Irregular clusters of endocrine cells scattered throughout the tissue of the pancreas that secrete insulin and glucagon. Also called islands of Langerhans.

is·lets of Lan·ger·hans

(ī'lĕts lahng'er-hahnz)
Cellular masses varying from a few to hundreds of cells lying in the interstitial tissue of the pancreas; they are the source of insulin and glucagon.

Islets of Langerhans

INSULIN secreting collections of cells lying in the INTERSTITIAL tissue of the PANCREAS. (Paul Langerhans, 1847–1888, German medical student, later anatomy professor).

islets of Langerhans

groups of cells found scattered in the pancreas of jawed vertebrates.

Islets of Langerhans

Special structures in the pancreas responsible for insulin secretion among other functions. They are named for Paul Langerhans, the German researcher who first identified them in 1869.

Langerhans,

Paul, German anatomist, 1847-1888.
islets of Langerhans - cellular masses composed of different cell types that comprise the endocrine portion of the pancreas and are the source of insulin and glucagon. Synonym(s): islet tissue; Langerhans islands; pancreatic islands; pancreatic islets
Langerhans cell granulomatosis
Langerhans cells - dendritic clear cells in the epidermis that are active participants in cutaneous delayed hypersensitivity.
Langerhans granule - a small membrane-bound granule first reported in Langerhans cells of the epidermis. Synonym(s): Birbeck granule
Langerhans islands - Synonym(s): islets of Langerhans

is·lets of Lan·ger·hans

(ī'lĕts lahng'er-hahnz)
Cellular masses consisting of several to several hundred cells lying in interstitial pancreatic tissue.
References in periodicals archive ?
The improved macrobead function following the second implant emphasizes the requirement to achieve a critical mass of islet tissue for optimal islet function.
Development of islet tissue showed a strong association with mesenchymal tissue as well as with ductal epithelium in early postnatal period, suggesting a strong role of ductal epithelium and mesenchymal tissue in the genesis of islet tissue.
Islet cell transplantation evolved out of a desire to make use of viable islet tissue from otherwise nonviable whole glands.
This requires a better understanding of islet biology and the "basement membrane" of islet tissue. The researchers recommend combining many strategies supporting understanding of the need to maintain islet structural integrity and to provide a viable environment for islet preservation.
Although surgeons currently transplant islet tissue from deceased donors into female and male patients with type 1 diabetes, this therapy is hampered by a woeful shortage of suitable donations and by complications resulting from host-versus-graft disease.