ICA

(redirected from islet cell antibody)
Also found in: Dictionary, Encyclopedia.

ICA

Abbreviation for internal carotid artery.

islet autoantibodies

, islet cell antibodies,

ICA

Antibodies formed against insulin, glutamic acid decarboxylase, or protein tyrosine phosphatase-like molecules. They are serum markers for type 1 diabetes mellitus (DM). Children whose parents have type 1 DM and who have these markers present in their serum have a high risk of developing type 1 DM.
References in periodicals archive ?
Assessment of precision, concordance, specificity, and sensitivity of islet cell antibody measurement in 41 assays.
[4] Nonstandard abbreviations: IDDM, insulin-dependent diabetes mellitus; ICA, cytoplasmic islet cell antibody; GAD65, 65-kDa isoform of glutamic acid decarboxylase; GAD65-ab, autoantibody directed to GAD65; IA2, islet antigen-2; IA2c, intracellular part of IA2; IA2c-ab, autoantibody directed to IA2c; MICA, human monoclonal islet cell antibody; SDS-PAGE, sodium dodecyl sulfate-polyacrylamide gel electrophoresis; and 95% CI, 95% confidence interval.
Combined analysis and single-step detection of [GAD.SUB.65] and IA2 autoantibodies in IDDM can replace the histochemical islet cell antibody test.