It consists of a single or multiple foci of fibrous tissue composed of irregular bone
trabeculae that can lead to weakness or pathological fracture of the affected bones.
Cerebral CT gives false positive results in 1/3 of patients because of irregular bone
formations of the skull base (12).
Clinical examination showed irregular mandibular crest with bone spurs and it was noticed that the cause of complaint was the pressure to the irregular bone
structures of mandible when the patient wore the lower denture.
Caption: Figure 2: CT-guided biopsy (a) showed irregular bone
structure with fibrotic marrow spaces ((b) H&E; original magnification x20) containing multinucleated giant cells ((c) arrowheads; chloroacetate esterase stain; original magnification x20).
Results of a computed tomography scan revealed an osteolytic left hemimandibular mass with irregular bone
production and a soft tissue mass in the left external auditory meatus.
It was observed that in the autogenous graft group, a numerous formation of dispersed and irregular bone
with multiple osteoids and limited inflammatory infiltrate in the study periods.
Bone cements have no intrinsic adhesive properties; they rely instead on close mechanical interlock between the irregular bone
surface and the prosthesis.
Review of pathology slides from outside biopsy revealed morphologic features similar to fibrous dysplasia (Figure 3A); however, on closer inspection at high power, malignant cells with round and spindle nuclei were identified infiltrating irregular bone
trabeculae with osteoid formation (Figure 3B).
Other abuse markers include fractures to ribs and at the front and back of the jaw, irregular bone
growth due to leg and neck injuries and a break at the end of the upper arm bone that is usually caused by violent twisting.
Using real-time RT-PCR we observed a significant down-regulation of collagen 1[alpha]1 mRNA in both bone types, long bone (tibia) as well as irregular bone
(vertebrae) of HFD mice.
Isolated irregular bone
frequently occur along various suture line in region of fontanelle and are called wormian bone named after Danish Anatomist" Wormius" They are usually in interparietal portion of occipital bone and remain separate throughout life forming large wormian bone called "OS INCA" (1).
The battered child's skull included a healed fracture, perhaps caused by a deliberate blow to the head; fractured ribs; irregular bone
growth caused by leg and neck injuries; and a break at the upper end of the arm, possibly attributed to being twisted.