ipriflavone


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ipriflavone

(ĭ″prĭ-flā′vōn)
A dietary supplement, 7-isopropoxyisoflavone, synthesized from the soy protein isoflavone daidzein. It is promoted as a treatment for osteoporosis.

ipriflavone (īˈ·pr·flāˑ·vōn),

n a synthetic isoflavone used to treat Paget's disease and to protect bones from damage due to osteoporosis, hyperparathyroidism, and corticosteroid therapies. Precaution advised for patients with renal disorders, lymphopenia, immunosuppression, gastrointestinal disorders, or a history of breast or reproductive cancers and those taking theophylline, caffeine, theobromine, phenytoin, warfarin, tolbutamide, NSAIDs, and immunosuppressant medications. Use of ipriflavone has also caused asymptomatic lymphopenia in test subjects, so regular blood cell counts are recommended during supplementation. Also called
7-isopropoxyisoflavone. See also isoflavones.
References in periodicals archive ?
Ostivone: Scientifically known as ipriflavone, Ostivone works synergistically, binding with calcium, to produce significantly greater bone mineral density when compared to using calcium alone.
Ipriflavone (IP) (7-isopropoxy-3-phenyl-4H-1-benzopyran-4-one) falls into the large group of isoflavonoids.
By contrast, in a large RCT, ipriflavone failed to show any skeletal improvement in postmenopausal women compared to the placebo group (Alexandersen et al.
Nutritional supplements are also available to address the condition, such as calcium, vitamin D, ipriflavone, magnesium and soy supplements, among others.
It contains Ipriflavone, Vitamin D and Calcium with Oyster Shell Extracts.
In the US, Ipriflavone is available as a nutritional supplement.
For example, in a study examining the effects of ipriflavone and vitamin D3 on BMD of the second metacarpal in a sample of chronic stroke patients (onset >1 year), the BMD on the paretic side decreased by 1.
None of the patients received any other medication that might affect calcium metabolism,such as ipriflavone, vitamin K, or aluminum hydroxide.
Ipriflavone and estriol, as well as the other substances mentioned in the article, are all available for sale under their generic names.
3) A well-designed trial in postmenopausal women found that ipriflavone, a synthetic phytoestrogen, did not decrease bone loss.
In a three-year study of nearly 500 postmenopausal women with slight osteoporosis, there was no significant change in bone density between the women who took just calcium supplements, and those who took calcium plus ipriflavone.