ionophore


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Related to ionophore: monensin

ionophore

 [i´on-o-for″]
any molecule, as of a drug, that increases the permeability of cell membranes to a specific ion.

i·on·o·phore

(ī-on'ō-fōr),
A compound or substance that forms a complex with an ion and transports it across a membrane.
[ion + G. phore, a bearer]

ionophore

(ī-ŏn′ə-fôr)
n.
A compound that facilitates the transport of ions across a cell membrane, either by binding with the ion or by creating a channel through the membrane.

ion·o·phore

(ī-on'ō-fōr)
A compound or substance that forms a complex with an ion and transports it across a membrane.
[ion + G. phore, a bearer]

ionophore

a compound that can increase the permeability of cell membranes to ions. Channel-forming ionophores form pores in the membrane allowing the passage of different ions, whilst mobile carrier ionophores diffuse in the membrane and can be ion-specific.
References in periodicals archive ?
Ionophores, such as sodium monensin (MON), are among the most studied feed additives for ruminant diets.
Meanwhile, several compounds have been shown as selective for metal analysis and used as receptors for the design of sensing systems, ranging from alloys and amalgam [8] and synthetic metal ionophores [9, 10] to biological receptors [9, 11].
Omar, "Structural, optical and sensing properties of ionophore doped graphene based bionanocomposite thin film," Optik, vol.
Albeit there are a few patch-clamp studies on granulocytes which provide valuable information, they can be associated with possible limitations as electrophysical measurements in neutrophils are difficult by nature, for example, description of NADPH oxidase of other cells (eosinophils [16, 19, 24], the granulocytic cell line HL-60 [21, 22], or macrophages [15]), application of intracellular milieu changing ionophores (e.g., valinomycin, gramicidin, and amphotericin) [11, 18, 23], or the use of enucleated neutrophils [17, 20].
For detection of phosphorylated ERK1/2, C57BL/6-derived BMCMCs were stimulated with 50 ng/mL PMA plus 10 [micro]M A23187 calcium ionophore or 5 [micro]M of either [Pam.sub.2][CysK.sub.4], CL264, [Pam.sub.2][CysK.sub.4] plus CL264, CL401, CL413, or CL531 for 5 min at 37[degrees]C and 5% C[O.sub.2].
Mauel, "Macrophage activation for intracellular killing as induced by calcium ionophore: Correlation with biologic and biochemical events," The Journal of Immunology, vol.
Matt, Flow-Injection Potentiometry by Poly(vinyl chloride)-Membrane Electrodes with Diphosphoryl-dicarboxylicacid-p-tert- butylcalix[4] arene Ionophore for the Determination of Th(IV) Ions, Anal.
The biggest category of antibiotic they use are in the ionophore class of compounds that control parasites while having antibiotic effects.
Lipopolysaccharide (LPS), TNF-[alpha], and calcium ionophore rapidly induce the differentiation of blood monocytes into DC-like cells [12].
The use of feed additives, mainly ionophore antibiotics, has become common aiming to increase meat production, reduce or prevent diseases, reduce the age at slaughter and, consequently, improve the quality of animal derived foods (Prado, 2010a; Valero et al., 2011; Zawadzki et al., 2011a and b).
Propofol activates GABA A receptors-chloride ionophore complex in dissociated hippocampal pyramidal neurons of the rat.