As Hellmich makes clear, ion channels
are not simple holes.
Figure S2: comparison of ion channel
currents in cells after different differentiation times.
where [g.sub.Na.sup.max]=120mS[cm.sup.-2] and [g.sub.K.sup.max]=36mS[cm.sup.-2] is the maximal conductance of the corresponding ion channel
. [[chi].sub.i] i=(Na, K) is a scaling factor, which equals to the ratio of active (non-blocked) i-type ion channel
numbers to total itype ion channel
number within a given membrane size [30, 31].
In this part, a numerical calculation is used to analyze the effects of the inner and outer radii on the dispersion curves of the azimuthally symmetric (l = 0) ES and TM modes and the interaction between them under different EM characteristics of the ion channel
. For the convenience of the numerical calculation, The dispersion frequency [omega] and the wavenumber [k.sub.z] are normalized by the beam frequency [[omega].sub.b] and the speed of the light in vacuum; that is, [mathematical expression not reproducible].
Stockand, "Restrictive expression of acid-sensing ion channel
5 (Asic5) in unipolar brush cells of the vestibulocerebellum," PLoS One, vol.
The prediction for ion channel
types of the conotoxins requires that the protein sequences are represented by the eigenvectors of the same number of dimension.
There is a huge diversity of ion channels
in both the outer and inner mitochondrial membrane (OMM, IMM).
Dr Charles Large, chief executive officer for Autifony, said: "Novel and more effective treatments for schizophrenia are desperately needed and the ion channels
that we are targeting are closely implicated in brain circuits which are believed to be dysfunctional in schizophrenia.
By combining the microfluidic Cytocentering technology with a sophisticated liquid handling system and an all new digital amplifier with both voltage- and current clamp capabilities, the CytoPatch2 can record whole cell and single channel currents, and works equally well for voltage gated ion channels
(constant perfusion mode) and ligand gated ion channels
(fast solution exchange, <4ms compound wash-in, <10ms wash-out).
longibrachiatum was linked to increased permeability, via voltage-dependent sodium and potassium ion channels
, in some sperm cellular membranes.
The disease, which can cause arrhythmias that lead to seizures and sudden death, is caused by a mutation in any of various genes encoding cardiac ion channels
or their associated proteins.
Since the CFTR gene discovery, hundreds of mutations have been identified, including G551D, which results in a protein that disrupts the ion channel
function of the cystic fibrosis protein.