jod-Basedow phenomenon

(redirected from iodine-induced hyperthyroidism)

Jod-Ba·se·dow phe·nom·e·non

(bahs'ĕ-dof), Jod is the German word for iodine, not a proper name.
induction of thyrotoxicosis in patients previously euthyroid as a result of exposure to large quantities of iodine; occurs most often in geographic areas of endemic iodine-deficient goiter and in patients with multinodular goiter; can also develop following use of iodine-containing agents for diagnostic studies.
Farlex Partner Medical Dictionary © Farlex 2012


Karl Adolph von, German physician, 1799-1854.
Basedow disease - Synonym(s): Graves disease; thyrotoxicosis
Basedow goiter - colloid goiter which becomes hyperfunctional after the ingestion of excess iodine, causing Jod-Basedow phenomenon.
Basedow pseudoparaplegia - weakness of the thigh muscles in thyrotoxicosis.
Basedow syndrome - myeloneuropathy seen in the presence of thyrotoxicosis.
Jod-Basedow phenomenon - induction of thyrotoxicosis in a previously euthyroid individual as a result of exposure to large quantities of iodine. Synonym(s): iodine-induced hyperthyroidism
Medical Eponyms © Farlex 2012

jod-Ba·se·dow phe·nom·e·non

(yod-bah'zĕ-dō fĕ-nom'ĕ-non)
Induction of thyrotoxicosis in patients previously euthyroid as a result of exposure to large quantities of iodine.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
The radioactive iodine assessment should help to distinguish Graves' hyperthyroidism from iodine-induced hyperthyroidism. Iodine-induced hyperthyroidism can last from one month to 18 months and is treated by discontinuing iodine and, if indicated, administering a beta-adrenergic antagonist, such as atenolol.
In the setting of iodine-induced hyperthyroidism with low radionuclide uptake, thyroid gland ablation with radioactive iodine is not a viable option as the gland is already saturated with iodine [17].
We considered the diagnosis of toxic adenoma/toxic nodular goiter/Graves' disease before and after the introduction of mandatory iodization in Ghana in 1996, to demonstrate the possible presence of iodine-induced hyperthyroidism; we considered diagnosis of Hashimoto's thyroiditis and Graves' disease before and after 1996 to demonstrate a link between the administration of iodine and thyroid autoimmunity.
Iodine-induced hyperthyroidism: Iodine overload in pregnancy and in the neonatal period usually leads to hypothyroidism (39).
Interleukin-6 (IL-6), a cytokine associated with inflammation, was proposed as a biomarker to distinguish between amiodarone-induced thyroiditis and iodine-induced hyperthyroidism. Marked elevations of IL-6 levels correlated closely with subacute thyroiditis in patients without preexisting thyroid disease.
Tables 2 and 4 show the percent of infants and mothers at risk of iodine-induced hyperthyroidism (IIH).
A main complication observed after initiation of iodine prophylaxis is iodine-induced hyperthyroidism, which has been reported in many iodine supplementation programs (21,22).
Iodine toxicity may result in a variety of conditions ranging from fetal and neonatal hypothyroidism and goitre, iodine-induced hyperthyroidism, thyroid underactivity, papillary thyroid cancer and an increased incidence of autoimmune thyroid disorders such as Hashimoto and Graves Disease (Dorea, 2002; International Council for the Control of Iodine Deficiency Disorders, 2001)
Low radioiodine uptake has also been seen in some conditions associated with thyroid hyperfunction such as thyrotoxicosis factitia (that is due to exogenous thyroid hormone) and iodine-induced hyperthyroidism. (3) The test may be performed when the following disorders are present: colloid nodular goiter, Graves disease, silent thyroiditis, and toxic nodular goiter.
A critical evaluation of some review articles on iodineinduced hypothyroidism and iodine-induced hyperthyroidism reveals that in most cases, organic forms of iodine are involved.