iobenguane

[i″o-ben´gwān]

a norepinephrine analogue that is taken up by the neuroendocrine cells and concentrated in the hormone storage vesicles; labeled with radioactive iodine, it is used for diagnostic imaging of neuroendocrine tumors and disorders of the adrenal medulla.

References in periodicals archive ?

AZEDRA (iobenguane I 131) 555 MBq/mL injection for intravenous use, Ultra-orphan Radiotherapeutic

Progenics Pharmaceuticals Announces Second Quarter 2019 Financial Results and Business Update

The company said MRT is an effective form of therapy that uses radiopharmaceuticals including Lutathera (Lu-177 DOTATATE) and Azedra (I-131 iobenguane) to target tumors based on certain receptors that these tumors express.

MIM Software Inc awarded US FDA's 510(k) clearance for molecular radiotherapy dosimetry

TUESDAY, July 31, 2018 (HealthDay News) -- Azedra (iobenguane) has been approved by the U.S.

FDA Approves Azedra for Rare Adrenal Tumors; First systemic treatment for patients who experience tumor-related symptoms such as hypertension

It also provides an exclusive AdreView planar application for automated heart to mediastinum ratio generation for Iobenguane I-123 images and the Dosimetry Toolkit for a quantitative SPECT and Planar calculation of the Radioisotope Therapy planning value.

XELERIS WORKSTATION IMPROVES CLINICAL CAPABILITIES

(NASDAQ: MIPI), Cambridge, Mass., has initiated a Phase 2a clinical trial of Azedra (Ultratrace(tm) iobenguane I-131 or Ultratrace MIBG) for the treatment of children with high-risk neuroblastoma, a neuroendocrine cancer that primarily affects children.

MOLECULAR INSIGHT INITIATES PHASE 2A AZEDRA CLINICAL TRIAL

* There are insufficient data to recommend PET scanning or radionuclide imaging (with iodocholesterol or iobenguane sulfate 1-123) in the evaluation of incidentally detected adrenal masses.

Incidental adrenal masses. (The Effective Physican)

Imaging techniques (iodine 131 iobenguane sulfate I 123) greatly facilitate tumor localization and surgical planning.

Pigmented Cardiac Paraganglioma

AZEDRA (iobenguane I 131) is indicated for the treatment of adult and pediatric patients 12 years and older with iobenguane scan positive, unresectable, locally advanced or metastatic pheochromocytoma or paraganglioma who require systemic anticancer therapy.

Progenics Pharmaceuticals, Inc. - CMS Grants New Technology Add-On Payment for Inpatient Use of AZEDRA

The Azedra (iobenguane I 131) injection for intravenous use has been approved by the US FDA for the treatment of adults and adolescents age 12 and older with rare tumours of the adrenal gland (pheochromocytoma or paraganglioma) that cannot be surgically removed (unresectable), have spread beyond the original tumour site and require systemic anticancer therapy.