involucrin

in·vo·lu·crin

(in'vō-lū'krin), [MIM*147360]
A non-keratin soluble cross-linked protein present on the cytoplasmic aspect of the plasmalemma of a squama.
[fr. L. involucrum, a wrapper]

involucrin

a structural protein synthesized in the stratum spinosum of the epidermis.
References in periodicals archive ?
Decreased expression of retinoic acid receptors, transforming growth factor beta, involucrin, and comifin in cervical intraepithelial neoplasia.
It reinforces the corneocyte envelope (synthesis of involucrin, transglutaminase and tight junctions), and the intercellular cement by lipid production (ceramides and cholesterol) ensuring the skin barrier function.
Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes.
Along with the response to RA, there was an associated increase in levels of involucrin and filaggrin at the protein level as demonstrated with immunofluorescent labelling.
3], keratinositlerde hucre proliferasyonunu suprese ederek involucrin ve transglutaminaz-1 gibi diferansiyasyon molekullerini indukler ve kornifiye hucre zarfi olusumunu artirir.
Time permitting, the study will be extended to also investigate the presence of an additional protein, involucrin, which is the substrate for the TGasel enzyme.
High-cell-density phorbol ester and retinoic acid upregulate involucrin and downregulate suprabasal keratin 10 in autocrine cultures of human epidermal keratinocytes.
Comments: Developed from pomegranate peel, Adandrine completely inhibits the growth of fungus Malassezia furfur, restores the balance of the epidermal differentiation process by boosting the synthesis of involucrin and strengthens the function barrier.
III] Glucose phosphate GPI Glucose-6-phosphate isomerase isomerase activity, cytokine activity Growth factor, augmenter GFER Cell proliferation of liver regeneration Hect domain and RLD 6 HERC6 Ubiquitin cycle Homeodomain interacting HIPK3 Protein kinase activity protein kinase 3 Interleukin-8 IL8 Cytokine activity Involucrin IVL Keratinocyte differentiation SRY (sex determining SOX15 Transcription factor region Y)-box 15 activity Mitogen-activated protein MAP3Kl1 JNK cascade kinase kinase kinase 11 DC0717-S-0282 (a) S100 calcium binding S100A8 Inflammatory response protein A8 Gene names and symbols are from UniGene (http://www .
Compared with untreated cells, the sap-enhanced cells showed more than a 100-fold surge in production of involucrin, a protein for forming cell layers, and a 50% increase in filaggrin, another protein that boosts skin moisture.
The SC is made up of corneocytes: terminally differentiated keratinocytes, highly cross-linked by transglutaminases with cornified envelope proteins such as loricrin, involucrin, filaggrin, and small proline-rich proteins.