Western blot analysis was used for analyzing the protein levels of loricrin and involucrin
in skin lesions.
Expression of cornification-related molecules including involucrin
, filaggrin, caspase 14 and calcium-sensing receptor was higher in the AH
Unilateral psoriasis: a case individualized by means of involucrin
Modulation of keratin 1, 10 and involucrin
expression as part of the complex response of the human keratinocyte cell line HaCaT to ultraviolet radiation," Interdisciplinary Toxicology, vol.
On the other hand, in keratinocytes exposed to arsenic expression of involucrin
was decreased, a similar pattern being previously highlighted in human cSCC .
The SC is made up of corneocytes: terminally differentiated keratinocytes, highly cross-linked by transglutaminases with cornified envelope proteins such as loricrin, involucrin
, filaggrin, and small proline-rich proteins.
, a strong marker of cell differentiation, has similar localization patterns with hBD-1 and hBD-2 in gingiva.
Immunohisto chemical localization of cytokeratins and involucrin
in calcifying epithelioma: comparative studies with normal skin.
Keratin and involucrin
immunohistochemistry of nasopharyngeal carcinoma.
The intermediate filaments are assembled from keratin monomers and the cornified envelope is assembled from a protein called involucrin
and several other proteins.
26) KFAP's also known as intermediate filament associated proteins are composed of filaggrin, tricohyalin, desmosomal proteins and proteins of cornified cell envelope (loricrin, involucrin
and small proline rich proteins).
1,4 Some immunohistochemical markers have been introduced including Involucrin
, CEA and EMA.