intron

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Related to intronic: Intergenic

in·tron

(in'tron),
A portion of DNA that lies between two exons, is transcribed into RNA, but does not appear in that mRNA after maturation because the intron is removed and the exons spliced together, and so is not expressed (as protein) in protein synthesis. By customary usage, the term is extended to the corresponding regions in the primary transcript of mRNA before maturation.
[inter- + -on]

intron

/in·tron/ (in´tron) a noncoding sequence between two coding sequences within a gene, processed out in the formation of mature mRNA.

intron

(ĭn′trŏn)
n.
A segment of a gene situated between exons that is removed before translation of messenger RNA and does not function in coding for protein synthesis.

intron

[in′tron]
Etymology: L, intra, within, regin, region
a sequence of nucleotides in eukaryotic DNA that does not code for amino acids and interrupts the coding sequence of a gene. Some genes contain numerous long introns. Compare exon.

in·tron

(in'tron)
A portion of DNA that lies between two exons, is transcribed into RNA, but does not appear in that RNA after maturation, and so is not expressed (as protein) in protein synthesis.

intron

A non-coding segment of a DISCONTINUOUS GENE. Introns are lengths of DNA interposed between coding segments (EXONS) in a gene and are transcribed into MESSENGER RNA but are then removed from the transcript and the exons spliced together. Introns do not contain biological information.

intron

or (‘in’ for intervening) - an intervening nucleotide sequence in an INTERRUPTED split gene. Such sequences are transcribed into primary RNA transcripts, but then excised from the RNA, leaving behind the EXON sequences for the functional gene product. See RNA PROCESSING, RNA SPLICING.

intron

untranslated, intervening sequences that are interspersed between coding sequences of a particular gene of almost all eukaryocytic genes and which are excised from the primary RNA transcript to yield mRNA.

intron-exon junction
introns are removed by the catalytic action of small nuclear riboproteins (snRNPs) which bind to special recognition sequences at the 5,(donor junction) and 3,(receptor junction) to form a complex called a spliceosome.
References in periodicals archive ?
Coding regions with 10-bp flanking intronic sequences of genes of interest were enriched using the SureSelectXT Target Enrichment System (Agilent Technologies) for Illumina Paired-End Sequencing Library.
Furthermore, research demonstrates that UTRs as well as coding and intronic regions are targeted by miRNA for translational suppression of mRNA transcripts (29-31).
We identified nine unique SNPs located in different exonic and intronic regions of the [[beta].
Here we report eight polymorphisms in exons and two genetic variations in intronic regions.
A haplotype that was initially linked to T2DM included an intronic A to G mutation at position 43, which appears to be involved in CAPN10 transcription.
All missense mutations, insignificant mutations and potential intronic mutations which may affect RNA function determined as a result of molecular analysis are shown in Table 1.
p53 intronic G13964C variant in colon cancer and its association with HPV.
Primers were designed to amplify eight segments between 200 and 400 pb (table 1) of the exonic and intronic regions adjacent to Shh exons.
2) It is likely that some patients may have mutations in the regulatory, promoter, or intronic regions of the enzyme gene, which has not yet been identified.
1971; Bussolati and Pearse, 1967), it seems plausible that these intronic polymorphisms affect intracellular molecular pathways eventually manifesting as SF.
The study, "Bifunctional RNAs Targeting the Intronic Splicing Silencer Nl Increase SMN Levels and Reduce Disease Severity in an Animal Model of Spinal Muscular Atrophy," was published in the journal Molecular Therapy.
With the above background, a Japanese group found that their population has shown higher incidence of osteoarthritis in patients having intronic and core promoter SNP in CALM-1 gene (48).