intron


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in·tron

(in'tron),
A portion of DNA that lies between two exons, is transcribed into RNA, but does not appear in that mRNA after maturation because the intron is removed and the exons spliced together, and so is not expressed (as protein) in protein synthesis. By customary usage, the term is extended to the corresponding regions in the primary transcript of mRNA before maturation.
[inter- + -on]

intron

/in·tron/ (in´tron) a noncoding sequence between two coding sequences within a gene, processed out in the formation of mature mRNA.

intron

(ĭn′trŏn)
n.
A segment of a gene situated between exons that is removed before translation of messenger RNA and does not function in coding for protein synthesis.

intron

[in′tron]
Etymology: L, intra, within, regin, region
a sequence of nucleotides in eukaryotic DNA that does not code for amino acids and interrupts the coding sequence of a gene. Some genes contain numerous long introns. Compare exon.

in·tron

(in'tron)
A portion of DNA that lies between two exons, is transcribed into RNA, but does not appear in that RNA after maturation, and so is not expressed (as protein) in protein synthesis.

intron

A non-coding segment of a DISCONTINUOUS GENE. Introns are lengths of DNA interposed between coding segments (EXONS) in a gene and are transcribed into MESSENGER RNA but are then removed from the transcript and the exons spliced together. Introns do not contain biological information.

intron

or (‘in’ for intervening) - an intervening nucleotide sequence in an INTERRUPTED split gene. Such sequences are transcribed into primary RNA transcripts, but then excised from the RNA, leaving behind the EXON sequences for the functional gene product. See RNA PROCESSING, RNA SPLICING.

intron

untranslated, intervening sequences that are interspersed between coding sequences of a particular gene of almost all eukaryocytic genes and which are excised from the primary RNA transcript to yield mRNA.

intron-exon junction
introns are removed by the catalytic action of small nuclear riboproteins (snRNPs) which bind to special recognition sequences at the 5,(donor junction) and 3,(receptor junction) to form a complex called a spliceosome.
References in periodicals archive ?
Additionally, intron 1 was 2,398 bp, intron 2 was 735 bp, intron 3 was 118 bp, intron 4 was 1,325 bp, intron 5 was 94 bp, intron 6 was 1,307 bp, intron 7 was 606 bp, and intron 8 was 734 bp.
1 that possibly insertion of first intron (809 bp) and second exon (707 bp) has taken place in humans and similarly insertion of first intron (809 bp) and second exon (704 bp) has taken place in chimps some 6-10 million years ago, i.
In addition, the more conserved sequences of the flanking exons can be used to design PCR primers that amplify the intron (Lessa 1992, Corte-Real et al.
The spliceosome components seem to have evolved from group II intron mRNAs and the Sm protein domain, which is involved in RNA-processing reactions in archaea.
VFR is pleased to have this opportunity to work with INTRON and anticipates a long and close relationship with mutual success for both companies in India," Hernik added.
Once the introns are removed, the spliceosome can stitch together exons in various combinations.
Further, in order to understand if the copy numbers in some respect relates to the size of gene, intron and exon, correlation coefficients (r) were calculated.
Analyses of the intron 4 variable number of tandem repeats (VNTR) polymorphism, the E298A polymorphism in exon 7, and the G10-T polymorphism in intron 23 of the ecNOS gene were performed as we have previously described (15).
INTRON A is a recombinant version of naturally occurring alpha interferon, which has been shown to exert both antiviral and immunomodulatory effects.
The sustained response rate increases from 12% with Intron alone to 41% when ribavirin is added, so it would seem logical that it would help to add ribavirin to PEG-Intron.
They found that all of the chickens' sequences were shorter because they contain shorter introns, the regions of genes that contain so-called nonsense, or noncoding, DNA.
Group I intron encoded endonuclease site" is interpreted to mean a segment of DNA having a sequence that is recognized by a Group I intron encoded endonuclease and, as shown in Figure 6 of the '605 patent, that includes the insertion site for the corresponding Group I intron.