intraventricular injection

in·tra·ven·tric·u·lar in·jec·tion

the introduction of materials for diffusion throughout the ventricular and subarachnoid space by means of ventricular puncture.
Farlex Partner Medical Dictionary © Farlex 2012

in·tra·ven·tric·u·lar in·jec·tion

(intră-ven-trikyū-lăr in-jekshŭn)
Introduction of materials for diffusion throughout ventricular and subarachnoid space with ventricular puncture.
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Intraventricular injection of 8-Br-cADPR (5, 10, and 20 nmol) significantly prolonged convulsion latency (P = 0.037, 0.034, and 0.000, respectively), reduced convulsion duration (P = 0.005, 0.005, and 0.005, respectively), and reduced convulsion behavior scores (P = 0.015, 0.015, and 0.000, respectively).
Intraventricular injection was performed as previously described[sup][12] with slight modifications.
According to a previous pharmacological study, the maximum convulsive dose of ropivacaine is 33.8 mg/kg in rats.[sup][19] Therefore, 30 min after intraventricular injection, rats in the ropivacaine and ropivacaine+8-Br-cADPR groups were intraperitoneally injected with 33.8 mg/kg of 0.5% ropivacaine dissolved in 10 ml of normal saline solution.
Intraventricular injection of 8-Br-cyclic ADP-ribose reduces convulsion behavior scores, prolongs latency, and shortens duration of ropivacaine-induced convulsion
Intraventricular injection of 8-Br-cyclic ADP-ribose reduces electroencephalography spike waves
Intraventricular injection of 8-Br-cyclic ADP-ribose reduces CD38 and cyclic ADP-ribose levels following ropivacaine-induced convulsion
Intraventricular injection of 8-Br-cADPR (5, 10, and 20 nmol) significantly reduced intracellular cADPR levels compared to the ropivacaine group ( P = 0.026, 0.035, and 0.016, respectively).
Intraventricular injection of 8-Br-cyclic ADP-ribose inhibits apoptosis following ropivacaine-induced convulsion
The most aggressive treatment is intrathecal lumbar or intraventricular injection of chemotherapeutic drugs such as methotrexate and cytosine arabinoside or liposomal cytarabine.
In an animal model of Alzheimer's Disease (AD) induced by intraventricular injection of streptozocin, Rhalili et at showed that administration of crocin resulted in significantly better results in passive avoidance test 3'.
-- Intraventricular injection of a gene for vascular endothelial growth factor-2 can now be performed on an outpatient basis, and the new technique has been shown in a placebo-controlled study to produce demonstrable revascularization of the ischemic myocardium.
The use of Adenoviral vectors (Ad-vectors) encoding GFP (Green Fluorescent Protein) or various other marker proteins, for example RFP (Red Fluorescent Protein), is very useful for many studies in the central nervous system including tract-tracing studies (1-2), intraventricular injections (3) or ex vivo cell labelling for cell transplantation purposes.
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