Within any tubule.
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A landmark in our understanding of testicular germ cell tumors occurred in the 1970s when, in a series of papers, Skakkebaek (2-5) convincingly demonstrated the intratubular cellular precursor to the great majority of germ cell tumors of young men.
Dynamic intratubular biomineralization following root canal obturation with pozzolan-based mineral trioxide aggregate sealer cement.
Both seminoma and nonseminoma tumors are believed to be derived from carcinoma in situ (CIS), also known as intratubular germ cell neoplasia (ITGCN), where the generation and expansion of tumor cells is restricted in the seminiferous tubules.
The renal histopathology was quantified for the degree of Bowman's space enlargement, tubular cell necrosis, exfoliated cells in the lumen, vascular congestion, and intratubular casts (8).
Microscopically, they are subdivided into intratubular or diffuse categories based on the organization of the neoplastic cells.
This Endoseal MTA is calcium-silicate based with a chemical composition very similar to that of MTA.[9] Endoseal is known for its intratubular biomineralization, high radiopacity, low solubility in contact with tissue fluids and expansion during setting and excellent viscosity for insertion.
Nevertheless, patients undergoing periodontal therapy often report experiencing discomfort in the form of dentinal hypersensitivity (DH), characterized by a short sharp pain that can be explained by the theory proposed by Brannstrom in 1966, which propound that a stimulus-induced shift in the movement of the intratubular fluid (either inward or outward) can activate pulpal nociceptor, resulting in pain (2,3).
(47) Nephrotoxicity due to protease inhibitors (PIs), mainly indinavir and atazanavir, is related to the formation of urolithiasis and intratubular precipitation, obstructive nephropathy, and acute or chronic interstitial nephritis.
Intratubular germ cell neoplasia of the human testis: heterogeneous protein expression and relation to invasive potential.
(26) Myoglobin causes tubular obstruction by interacting with Tamm--Horsfall proteins and forms intratubular casts.