intrathecal

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intrathecal

 [in″trah-the´kal]
1. within a sheath.
2. through the theca of the spinal cord into the subarachnoid space.

in·tra·the·cal

(in'tră-thē'kăl),
1. Within a sheath.
2. Within either the subarachnoid or the subdural space.

intrathecal

adjective Within a sheath; specifically, the spinal canal (in the subarachnoid or subdural space).

intrathecal

adjective Within a sheath, specifically, the spinal canal–in the subarachnoid or subdural space

in·tra·the·cal

(IT) (in'tră-thē'kăl)
1. Within a sheath.
2. Within the subarachnoid or subdural space.

intrathecal

1. Within a sheath.
2. Within the SUBARACHNOID SPACE.

Intrathecal

Introduced into or occurring in the space under the arachnoid membrane which covers the brain and spinal cord.
Mentioned in: Muscle Relaxants

in·tra·the·cal

(IT) (in'tră-thē'kăl)
Within a sheath.
References in periodicals archive ?
In humans, lower doses may be used intrathecally. [13] Short-term analgesic effects were observed in rats treated with 0.2, 0.4, 0.8, and 1.6 mg/kg ketamine intrathecal administration.
High incidence of pruritus varying between 20% to 90% has been reported following the use of sufentanil intrathecally in some of the studies.
Hoka, "Neurotoxicity of intrathecally administered bupivacaine involves the posterior roots/posterior white matter and is milder than lidocaine in rats," Regional Anesthesia and Pain Medicine, vol.
In the mechanical withdrawal threshold testing, groups of rats were injected intrathecally with saline, najanalgesin, or SP600125; the paw withdrawal threshold was measured for 24 h after injection.
To compare the subarachnoid block characteristics (onset and duration of sensory and motor block) 5[micro]g and 10[micro]g dexmedetomidine was added to 15mg 0.5% hyperbaric bupivacaine given intrathecally for spinal anesthesia.
Respiratory rate decreased significantly with all three doses of xylazine and returned to normal after 90 105 and 120 minutes with 6 8 and 10 mg/kg respectively Similar effects of xylazine have been reported by Nolan and Erhardt (1990) who reported that a2 agonist xylazine produced a dose-dependent decrease in mean arterial blood pressure in conscious rabbits when injected intrathecally through a cannula previously implanted under general anaesthesia.
They are done both intravenously and intrathecally (into the spinal canal).
(7), (8) Boschi et a1 (13) found that antipsychotics cause hypothermia in rats when the drug is administered intraperitoneally but not when given intrathecally. Perhaps for these reasons, in the early 1950s, before its psychotropic properties were known, chlorpromazine was used during surgery to induce artificial hibernation and suppress the body's response to cooling.
A total of 80 x [10.sup.6] cell were transplanted intrathecally and intramuscularly.
The clonidine group received bupivacaine 10 mg combined with 75 [micro]g of preservative free clonidine; the fentanyl group received bupivacaine 10 mg combined with 25 [micro]g fentanyl; and the placebo group received bupivacaine 10 mg combined with 0.5 mL distilled water, intrathecally. All patients received an intravenous preload of 5-7 mL/kg lactated Ringer's solution before a subarachnoid block.
All the patients underwent autologous BMMNCs intrathecally. Following cell therapy, patients underwent individualized neurorehabilitation.