Our laboratory has used high-fat diet to induce insulin resistance model and high-fat diet plus low-dose STZ intraperitoneal injection
to conduct T2DM model in wistar rats [13,17].
Our results show that the antinociceptive effects produced by intraperitoneal injection
OMT is reversed by NMDA, and were potentiated by coad-ministered MK801 and ifenprodil, while both alone in subthreshold doses did not show any effects on antinociception in mechanical allodynia test.
The experimental group consisted of two rats that received intraperitoneal injections
of pure ethanol (2 g/kg) diluted with normal saline (1:1 by volume).
Both non-diabetic and diabetic mice were subjected to various doses of insulin injections at 30 min after intraperitoneal injections
with borapetoside C (0.1 mg/kg) or with the vehicle.
Dexamethasone, which was dissolved in saline with 10% ethanol, was given to mice in the dexamethasone group by intraperitoneal injection
1 h before LPS administration.
Diabetes was induced by an intraperitoneal injection
of streptozotocin (65mg/kgBW) in DBC and DWT groups except the NC group.
The diabetic mice model was established by intraperitoneal injection
of streptozotocin (STZ) 40 mg/kg body weight.
C57BL/6J mice (16 weeks old) were randomly divided into 4 groups (n = 8/group) as follows: sham group, mice underwent sham surgery but without actual induction of TBI; TBI group, mice were injured using the TBI device; vehicle group, TBI mice were treated with 0.2 mL 20% dimethyl sulfoxide (DMSO; Roche, USA) by intraperitoneal injection
; SC560-treated group, TBI mice received intraperitoneal injection
of SC560 (5 mg/kg body weight; Cayman Chemical, USA) every day post-TBI surgery.
into groups of syngeneic A/J mice and TT extracts were administered three times per week for 14 days by intraperitoneal injection
. After removal of primary tumours and continuing treatment for 2 weeks, the level of spontaneous liver and lymph node metastasis was analysed by measuring the weights of affected organs.
At the age of 5 weeks and weight 25-30 g, the mice were anesthetized by intraperitoneal injection
with 1.25% citosol (Kyorin Pharmaceuticals, Tokyo, Japan) and instilled with an intratracheal application with 100 [micro]L ufCB (200 [micro]g/100 [micro]L/mouse) or LPS (1 [micro]g/[micro]L, 100 [micro]g/100 [micro]L/mouse; Sigma, St.
of 0.5% bupivacaine has been tried during laparoscopic cholecystectomy as well.
Rats were rendered diabetic by intraperitoneal injection
of streptozotocin (STZ (Sigma, Beijing, China), 50mg/kg) in citrate buffer, pH 6.3.