intramucosal carcinoma

intramucosal carcinoma

Oncology A high-grade/severe dysplasia–CIS of the GI mucosa, which extends to the lamina propria
References in periodicals archive ?
Optical coherence tomography to identify intramucosal carcinoma and high-grade dysplasia in Barrett's esophagus.
The majority, 33 patients, presented with a diagnosis of high-grade dysplasia, another 8 were diagnosed with intramucosal carcinoma, and 7 had both.
Some observers have defined intramucosal carcinoma as having a syncytial growth pattern, extensive back-to-back microglands, and intermingling of single cells and small clusters within the lamina propria.
13) This term encompasses cases in which the entire polyp head is replaced by carcinoma and adenomas with focal malignancy, but the definition excludes adenomas with highgrade dysplasia (intraepithelial carcinoma) or intramucosal carcinoma (invasive carcinoma limited to the lamina propria or invading no deeper than the muscularis mucosae) because these polyps possess negligible biologic potential for metastasis (14) (see Tis in note M).

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