Oral corticosteroids should be reserved for acute flares and for short periods, and intralesional therapy
may be especially useful for recalcitrant lesions (13).
Gottlieb said she was interested in the intralesional therapy
for her pediatric lupus patients with dystrophic calcifications.
Patients who failed the treatment were offered glucantime intralesional therapy
but were not followed further for the purpose of the study.
Surgical debridement and intralesional therapy
have been advocated, with endoscopy representing a less invasive option.
Eighty percent received intralesional therapy
, and 20% received intramuscular therapy in accordance with WHO recommendations (4).
Anderson Cancer Center in Houston, Texas, gave a presentation titled "Intralesional Therapy
for Systemic Disease: Implications for Success and Failure" at the HemOnc Today Conference in New York City.
In conjunction, professor Merrick Ross of the MD Anderson Cancer Center in Houston, Texas and a principal investigator for the Phase 2 study of PV-10 for metastatic melanoma, will give the presentation entitled "Intralesional therapy
: local/regional control and implications for systemic response."
For limited skin lesions, local therapy with liquid nitrogen, intralesional therapy
and local treatment with alitretinoin has been useful (16).
The mechanisms still need to be elucidated that underlie the synergistic tumouricidal effects described in the literature for both, treatment with chemotherapy (Etoposid, Paclitaxel) and Viscum, as well as through intralesional therapy
with Viscum in lymph node metastases.
Persistent treatment with proven topical and intralesional therapy
for refractory lesions should continue to be the mainstay of therapy for verruca vulgaris.
ACNE cysts can often be treated by intralesional therapy
(direct injection of a drug into the acne spot), which also helps to reduce scarring.